Tick-borne encephalitis virus infects rat astrocytes but does not affect their viability

Tick-borne encephalitis virus (TBEV) causes one of the most dangerous human neuroinfections in Europe and Asia. To infect neurons it must cross the blood-brain-barrier (BBB), and presumably also cells adjacent to the BBB, such as astrocytes, the most abundant glial cell type. However, the knowledge...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e86219
Hauptverfasser:	Potokar, Maja, Korva, Miša, Jorgačevski, Jernej, Avšič-Županc, Tatjana, Zorec, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actin Cytoskeleton - pathology Actin Cytoskeleton - virology Aedes albopictus Animals Arachnids Astrocytes Astrocytes - cytology Astrocytes - pathology Astrocytes - virology Biology Blood-brain barrier Brain Brain research Cell culture Cell death Cell Survival Cells (Biology) Cells, Cultured Cytoskeleton Dengue fever Encephalitis Encephalitis Viruses, Tick-Borne - physiology Encephalitis, Tick-Borne - pathology Encephalitis, Tick-Borne - veterinary Fluorescence Fluorescence microscopy Glial cells Health aspects Humans Immunology Infections International organizations Labeling Laboratories Mammalian cells Medical research Medicine Mobility Mosquitoes Muscle proteins Neurophysiology Physiology Rats Rats - virology Rats, Wistar Survival Tick-borne encephalitis Viability Virology Virus Internalization Viruses
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