A Novel Intergenic ETnII-[beta] Insertion Mutation Causes Multiple Malformations in Polypodia Mice

  Mouse early transposon insertions are responsible for ~10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of Polypodia, (Ppd), a spontaneous, X-linked dominant mutation with profound effects on body plan morphogenesis. Our new data shows that mutant mic...

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Veröffentlicht in:	PLoS genetics 2013-12, Vol.9 (12)
Hauptverfasser:	Lehoczky, Jessica, Thomas, Peedikayil, Patrie, Kevin, Owens, Kailey, Villarreal, Lisa, Galbraith, Kenneth, Washburn, Joe, Johnson, Craig, Gavino, Bryant, Borowsky, Alexander, Millen, Kathleen, Wakenight, Paul, Law, William, Keuren, Margaret, Gavrilina, Galina, Hughes, Elizabeth, Saunders, Thomas, Brihn, Lesil, Nadeau, Joseph, Innis, Jeffrey
Format:	Artikel
Sprache:	eng
Schlagworte:	Defects Deoxyribonucleic acid DNA DNA methylation Experiments Gene expression Morphogenesis Mutation Proteins
Online-Zugang:	Volltext
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