HIV-1 specific antibody titers and neutralization among chronically infected patients on long-term suppressive antiretroviral therapy (ART): a cross-sectional study

The majority of potent and broadly neutralizing antibodies against HIV-1 have been isolated from untreated patients with acute or chronic infection. To assess the extent of HIV-1 specific antibody response and neutralization after many years of virologic suppression from potent combination ART, we e...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e85371-e85371
Hauptverfasser:	Gach, Johannes S, Achenbach, Chad J, Chromikova, Veronika, Berzins, Baiba, Lambert, Nina, Landucci, Gary, Forthal, Donald N, Katlama, Christine, Jung, Barbara H, Murphy, Robert L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Analysis Anti-HIV Agents - therapeutic use Antibodies Antibodies, Neutralizing - blood Antibody response Antigenic determinants Antigens Antiretroviral agents Antiretroviral drugs Antiretroviral therapy B cells Binding Binding sites Biological products industry Biology Care and treatment Chronic infection Cross-Sectional Studies Development and progression Drug therapy Enzyme-Linked Immunosorbent Assay Epitopes Female Gastroenterology Glycoprotein gp120 Glycoprotein gp41 Glycoproteins Health aspects Highly active antiretroviral therapy HIV HIV Antibodies - blood HIV Infections - drug therapy HIV Infections - immunology HIV patients HIV-1 - genetics HIV-1 - immunology Human health and pathology Human immunodeficiency virus Humans Immunoglobulins Infection Infections Infectious diseases Life Sciences Male Medical diagnosis Medical research Medicine Middle Aged Neutralization Neutralizing Opsonization Patients Phagocytosis Ribonucleic acid RNA RNA, Viral - blood Vaccines Viral Load Viremia Virus diseases Viruses
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