Clustering gene expression regulators: new approach to disease subtyping

One of the main challenges in modern medicine is to stratify different patient groups in terms of underlying disease molecular mechanisms as to develop more personalized approach to therapy. Here we propose novel method for disease subtyping based on analysis of activated expression regulators on a...

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Veröffentlicht in:PloS one 2014-01, Vol.9 (1), p.e84955-e84955
Hauptverfasser: Pyatnitskiy, Mikhail, Mazo, Ilya, Shkrob, Maria, Schwartz, Elena, Kotelnikova, Ekaterina
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Sprache:eng
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