Infectious bursal disease virus influences the transcription of chicken γc and γc family cytokines during infection

Infectious bursal disease virus (IBDV) infection causes immunodeficiency in chickens. To understand cell-mediated immunity during IBDV infection, this study perform a detailed analysis of chicken γc chain (chCD132) and γc family cytokines, including interleukins 2, 4, 7, 9, and 15. The mouse anti-ch...

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Veröffentlicht in:	PloS one 2014, Vol.9 (1), p.e84503-e84503
Hauptverfasser:	Wang, Sanying, Teng, Qiaoyang, Jia, Lu, Sun, Xiaoyuan, Wu, Yongping, Zhou, Jiyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Biology Birnaviridae Infections - genetics Birnaviridae Infections - immunology Birnaviridae Infections - veterinary CD8 antigen Cell cycle Cell-mediated immunity Cellular communication Chickens Chickens - immunology Chickens - virology Cytokines Cytokines - genetics Disease E coli Embryo fibroblasts Fibroblasts Fibroblasts - virology Flow cytometry Fluorescence Gene Expression Regulation Immunity Immunofluorescence Infections Infectious bursal disease Infectious bursal disease virus - pathogenicity Infectious bursal disease virus - physiology Infectious diseases Interleukin Receptor Common gamma Subunit - genetics Interleukin Receptor Common gamma Subunit - immunology Interleukins Kinetics Laboratories Leukocytes (mononuclear) Lymphocytes Lymphocytes T Medicine Molecular weight Monoclonal antibodies Phenotype Polymerase chain reaction Poultry Poultry Diseases - genetics Poultry Diseases - immunology Poultry Diseases - virology Proteins Proteomics RNA polymerase Signal transduction Spleen T-Lymphocytes - metabolism Thymus Transcription Transcription, Genetic Veterinary Science Virology Viruses
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