Comparing the biological impact of glatiramer acetate with the biological impact of a generic

For decades, policies regarding generic medicines have sought to provide patients with economical access to safe and effective drugs, while encouraging the development of new therapies. This balance is becoming more challenging for physicians and regulators as biologics and non-biological complex dr...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e83757
Hauptverfasser:	Towfic, Fadi, Funt, Jason M, Fowler, Kevin D, Bakshi, Shlomo, Blaugrund, Eran, Artyomov, Maxim N, Hayden, Michael R, Ladkani, David, Schwartz, Rivka, Zeskind, Benjamin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates Analysis Animals Biological effects Biological products Biology Biomarkers Biomarkers - metabolism Cell Lineage - drug effects Cell Lineage - genetics Computation Computer applications Copolymer 1 Data collection Data processing Drug development Drugs Drugs, Generic - pharmacology Forkhead Transcription Factors - metabolism Gene expression Gene Expression Profiling Genes Genomes Genomics Glatiramer Acetate Identification methods Immune system Immune System - drug effects Immune System - metabolism Immunology Immunoregulation Laboratory animals Lymphocytes Lymphocytes T Medical personnel Medicine Mice Monocytes - cytology Monocytes - drug effects Monocytes - metabolism Multiple sclerosis Peptides - pharmacology Pharmaceuticals Physicians Receptors, G-Protein-Coupled - metabolism Regulators Splenocytes T cells T-Lymphocytes, Regulatory - drug effects T-Lymphocytes, Regulatory - immunology Transcription Up-Regulation - drug effects Up-Regulation - genetics
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