Alteration of the redox state with reactive oxygen species for 5-fluorouracil-induced oral mucositis in hamsters

Oral mucositis is often induced in patients receiving cancer chemotherapy treatment. It has been reported that oral mucositis can reduce quality of life, as well as increasing the incidence of mortality. The participation of reactive oxygen species (ROS) in the pathogenesis of oral mucositis is well...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-12, Vol.8 (12), p.e82834
Hauptverfasser:	Yoshino, Fumihiko, Yoshida, Ayaka, Nakajima, Atsushi, Wada-Takahashi, Satoko, Takahashi, Shun-suke, Lee, Masaichi Chang-il
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Fluorouracil Acetic acid Acids Animal models Animals Antioxidants Apoptosis Cancer Cancer therapies Care and treatment Cheek Cheek pouch Chemotherapy Cyclic N-Oxides - metabolism Cytokines Decay Decay rate Dentistry Deoxyribonucleic acid Disease Models, Animal DNA Drug development Drugs Electron paramagnetic resonance Electron spin Electron spin resonance Fluorouracil Fluorouracil - adverse effects Free radicals Glutathione Hamsters Health aspects Hospital costs In vivo methods and tests Kinetics Laboratory animals Lipid peroxidation Lipids Male Malondialdehyde Malondialdehyde - metabolism Medical research Mesocricetus Mucositis Organic acids Oxidation-Reduction Oxidative stress Oxygen Pathogenesis Peroxidation Pyrrolidines - metabolism Quality of life Rate constants Reactive oxygen species Reactive Oxygen Species - metabolism Redox properties Rodents Science Spin resonance Stomatitis Stomatitis - chemically induced Stomatitis - metabolism Stomatitis - pathology Thiobarbituric acid Ulcers University graduates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!