A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND)

Estimated glomerular filtration rate (eGFR), a measure of kidney function, is heritable, suggesting that genes influence renal function. Genes that influence eGFR have been identified through genome-wide association studies. However, family-based linkage approaches may identify loci that explain a l...

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Veröffentlicht in:	PloS one 2013-12, Vol.8 (12), p.e81888-e81888
Hauptverfasser:	Thameem, Farook, Igo, Jr, Robert P, Freedman, Barry I, Langefeld, Carl, Hanson, Robert L, Schelling, Jeffrey R, Elston, Robert C, Duggirala, Ravindranath, Nicholas, Susanne B, Goddard, Katrina A B, Divers, Jasmin, Guo, Xiuqing, Ipp, Eli, Kimmel, Paul L, Meoni, Lucy A, Shah, Vallabh O, Smith, Michael W, Winkler, Cheryl A, Zager, Philip G, Knowler, William C, Nelson, Robert G, Pahl, Madeline V, Parekh, Rulan S, Kao, W H Linda, Rasooly, Rebekah S, Adler, Sharon G, Abboud, Hanna E, Iyengar, Sudha K, Sedor, John R
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans - genetics Aged Body mass Cardiovascular disease Chromosome 10 Chromosome 15 Chromosome 20 Diabetes Diabetes mellitus Diabetic Nephropathies - genetics Diabetic nephropathy Diabetic retinopathy Diagnostic systems Epidemiology Epidermal growth factor receptors Ethnic factors European Continental Ancestry Group - genetics Female Genes Genetic Linkage Genetic Predisposition to Disease Genome-Wide Association Study Genomes Genotype Glomerular filtration rate Glomerular Filtration Rate - genetics Heritability Humans Identification methods Indians, North American - genetics Internal medicine Kidney diseases Kidney Diseases - genetics Linkage analysis Localization Male Medical research Medicine Mexican Americans - genetics Middle Aged Minority & ethnic groups Mortality Native Americans Nephropathy Pediatrics Polymorphism, Single Nucleotide Quantitative genetics Quantitative Trait Loci Renal function Single-nucleotide polymorphism Studies
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