Effects of intra-amniotic lipopolysaccharide and maternal betamethasone on brain inflammation in fetal sheep

Chorioamnionitis and antenatal glucocorticoids are common exposures for preterm infants and can affect the fetal brain, contributing to cognitive and motor deficits in preterm infants. The effects of antenatal glucocorticoids on the brain in the setting of chorioamnionitis are unknown. We hypothesiz...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-12, Vol.8 (12), p.e81644-e81644
Hauptverfasser:	Kuypers, Elke, Jellema, Reint K, Ophelders, Daan R M G, Dudink, Jeroen, Nikiforou, Maria, Wolfs, Tim G A M, Nitsos, Ilias, Pillow, J Jane, Polglase, Graeme R, Kemp, Matthew W, Saito, Masatoshi, Newnham, John P, Jobe, Alan H, Kallapur, Suhas G, Kramer, Boris W
Format:	Artikel
Sprache:	eng
Schlagworte:	Amniotic Fluid - drug effects Amniotic Fluid - immunology Analysis Animals Apoptosis Astrocytes Betamethasone Betamethasone - pharmacology Binding sites Biology Brain Brain research Children & youth Chorioamnionitis Cognitive ability Encephalitis - immunology Exposure Female Fetus - drug effects Fetuses Gestation Glucocorticoids Glucocorticoids - pharmacology Hippocampus Immune system Infants Infiltration Inflammation Injury prevention Lipopolysaccharides Lipopolysaccharides - pharmacology Magnetic resonance imaging Medical imaging equipment Medical research Mental health Microglia Mitogens Myelin Neurosciences Ovis aries Pediatrics Pregnancy Premature birth Premature infants Recruitment Sheep Steroids (Organic compounds) Substantia alba Synaptic vesicles Synaptophysin Uterus
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!