Relative risk of visceral leishmaniasis in Brazil: a spatial analysis in urban area
Visceral leishmaniasis (VL) is a vector-borne disease whose factors involved in transmission are poorly understood, especially in more urban and densely populated counties. In Brazil, the VL urbanization is a challenge for the control program. The goals were to identify the greater risk areas for hu...
Gespeichert in:
Veröffentlicht in: | PLoS neglected tropical diseases 2013-11, Vol.7 (11), p.e2540 |
---|---|
Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | 11 |
container_start_page | e2540 |
container_title | PLoS neglected tropical diseases |
container_volume | 7 |
creator | de Araújo, Valdelaine Etelvina Miranda Pinheiro, Letícia Cavalari Almeida, Maria Cristina de Mattos de Menezes, Fernanda Carvalho Morais, Maria Helena Franco Reis, Ilka Afonso Assunção, Renato Martins Carneiro, Mariângela |
description | Visceral leishmaniasis (VL) is a vector-borne disease whose factors involved in transmission are poorly understood, especially in more urban and densely populated counties. In Brazil, the VL urbanization is a challenge for the control program. The goals were to identify the greater risk areas for human VL and the risk factors involved in transmission.
This is an ecological study on the relative risk of human VL. Spatial units of analysis were the coverage areas of the Basic Health Units (146 small-areas) of Belo Horizonte, Minas Gerais State, Brazil. Human VL cases, from 2007 to 2009 (n = 412), were obtained in the Brazilian Reportable Disease Information System. Bayesian approach was used to model the relative risk of VL including potential risk factors involved in transmission (canine infection, socioeconomic and environmental features) and to identify the small-areas of greater risk to human VL.
The relative risk of VL was shown to be correlated with income, education, and the number of infected dogs per inhabitants. The estimates of relative risk of VL were higher than 1.0 in 54% of the areas (79/146). The spatial modeling highlighted 14 areas with the highest relative risk of VL and 12 of them are concentrated in the northern region of the city.
The spatial analysis used in this study is useful for the identification of small-areas according to risk of human VL and presents operational applicability in control and surveillance program in an urban environment with an unequal spatial distribution of the disease. Thus the frequent monitoring of relative risk of human VL in small-areas is important to direct and prioritize the actions of the control program in urban environment, especially in big cities. |
doi_str_mv | 10.1371/journal.pntd.0002540 |
format | Article |
fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1468585962</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A352850561</galeid><doaj_id>oai_doaj_org_article_5488702fc7344734b227cecc5e039244</doaj_id><sourcerecordid>A352850561</sourcerecordid><originalsourceid>FETCH-LOGICAL-c629t-ad52187969c2d4b1d6b81b1cb658e342ad2e42f84473208c066aad593a3b1d203</originalsourceid><addsrcrecordid>eNptkl2L1DAYhYso7rr6D0QLgngzY_Lmo6kXwrr4sbAg-HEd3qbpTMZMMybtwPrrTZ3uMgPSi5TkOScnh7conlOypKyibzdhjD365a4f2iUhBAQnD4pzWjOxgIqJh0f_Z8WTlDaEiFoo-rg4Aw6cV5U8L75_sx4Ht7dldOlXGbpy75KxEX3prUvrLfYOk0ul68sPEf84_67EMu2yJiOYA9zOp2NssC8xWnxaPOrQJ_tsXi-Kn58-_rj6srj5-vn66vJmYSTUwwJbAVRVtawNtLyhrWwUbahppFCWccAWLIdO5aQMiDJESsyamiHLMBB2Ubw8-O58SHruI2nKpRJK1BIycX0g2oAbvYtui_FWB3T630aIK41xcMZbLbhSFYHOVGy6kDcAlbHGCEtYndvKXu_n28Zma1tj-yG3dGJ6etK7tV6FvWYKSCWnuG9mgxh-jzYNejtV7T32NoxT7hpyZgCZ0VcHdIU5muu7kB3NhOtLJkAJIiTN1PI_VP5au3Um9LZzef9E8PpIsLboh3UKfhxc6NMpyA-giSGlaLv7Z1Kip-m7a1tP06fn6cuyF8cV3Yvuxo39BS481VY</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1492623226</pqid></control><display><type>article</type><title>Relative risk of visceral leishmaniasis in Brazil: a spatial analysis in urban area</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>Public Library of Science (PLoS)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>de Araújo, Valdelaine Etelvina Miranda ; Pinheiro, Letícia Cavalari ; Almeida, Maria Cristina de Mattos ; de Menezes, Fernanda Carvalho ; Morais, Maria Helena Franco ; Reis, Ilka Afonso ; Assunção, Renato Martins ; Carneiro, Mariângela</creator><contributor>Kamhawi, Shaden</contributor><creatorcontrib>de Araújo, Valdelaine Etelvina Miranda ; Pinheiro, Letícia Cavalari ; Almeida, Maria Cristina de Mattos ; de Menezes, Fernanda Carvalho ; Morais, Maria Helena Franco ; Reis, Ilka Afonso ; Assunção, Renato Martins ; Carneiro, Mariângela ; Kamhawi, Shaden</creatorcontrib><description>Visceral leishmaniasis (VL) is a vector-borne disease whose factors involved in transmission are poorly understood, especially in more urban and densely populated counties. In Brazil, the VL urbanization is a challenge for the control program. The goals were to identify the greater risk areas for human VL and the risk factors involved in transmission.
This is an ecological study on the relative risk of human VL. Spatial units of analysis were the coverage areas of the Basic Health Units (146 small-areas) of Belo Horizonte, Minas Gerais State, Brazil. Human VL cases, from 2007 to 2009 (n = 412), were obtained in the Brazilian Reportable Disease Information System. Bayesian approach was used to model the relative risk of VL including potential risk factors involved in transmission (canine infection, socioeconomic and environmental features) and to identify the small-areas of greater risk to human VL.
The relative risk of VL was shown to be correlated with income, education, and the number of infected dogs per inhabitants. The estimates of relative risk of VL were higher than 1.0 in 54% of the areas (79/146). The spatial modeling highlighted 14 areas with the highest relative risk of VL and 12 of them are concentrated in the northern region of the city.
The spatial analysis used in this study is useful for the identification of small-areas according to risk of human VL and presents operational applicability in control and surveillance program in an urban environment with an unequal spatial distribution of the disease. Thus the frequent monitoring of relative risk of human VL in small-areas is important to direct and prioritize the actions of the control program in urban environment, especially in big cities.</description><identifier>ISSN: 1935-2735</identifier><identifier>ISSN: 1935-2727</identifier><identifier>EISSN: 1935-2735</identifier><identifier>DOI: 10.1371/journal.pntd.0002540</identifier><identifier>PMID: 24244776</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Brazil - epidemiology ; Disease transmission ; Distribution ; Dogs ; Fatalities ; Health aspects ; Humans ; Infections ; Information systems ; Kala-azar ; Leishmaniasis, Visceral - epidemiology ; Leishmaniasis, Visceral - transmission ; Medical geography ; Parasitic diseases ; Risk Factors ; Socioeconomic factors ; Studies ; Urban Population</subject><ispartof>PLoS neglected tropical diseases, 2013-11, Vol.7 (11), p.e2540</ispartof><rights>COPYRIGHT 2013 Public Library of Science</rights><rights>2013 Araújo et al 2013 Araújo et al</rights><rights>2013 Araújo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Araújo VEMd, Pinheiro LC, Almeida MCdM, Menezes FCd, Morais MHF, et al. (2013) Relative Risk of Visceral Leishmaniasis in Brazil: A Spatial Analysis in Urban Area. PLoS Negl Trop Dis 7(11): e2540. doi:10.1371/journal.pntd.0002540</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c629t-ad52187969c2d4b1d6b81b1cb658e342ad2e42f84473208c066aad593a3b1d203</citedby><cites>FETCH-LOGICAL-c629t-ad52187969c2d4b1d6b81b1cb658e342ad2e42f84473208c066aad593a3b1d203</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820760/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820760/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2095,2914,23846,27903,27904,53770,53772,79347,79348</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24244776$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kamhawi, Shaden</contributor><creatorcontrib>de Araújo, Valdelaine Etelvina Miranda</creatorcontrib><creatorcontrib>Pinheiro, Letícia Cavalari</creatorcontrib><creatorcontrib>Almeida, Maria Cristina de Mattos</creatorcontrib><creatorcontrib>de Menezes, Fernanda Carvalho</creatorcontrib><creatorcontrib>Morais, Maria Helena Franco</creatorcontrib><creatorcontrib>Reis, Ilka Afonso</creatorcontrib><creatorcontrib>Assunção, Renato Martins</creatorcontrib><creatorcontrib>Carneiro, Mariângela</creatorcontrib><title>Relative risk of visceral leishmaniasis in Brazil: a spatial analysis in urban area</title><title>PLoS neglected tropical diseases</title><addtitle>PLoS Negl Trop Dis</addtitle><description>Visceral leishmaniasis (VL) is a vector-borne disease whose factors involved in transmission are poorly understood, especially in more urban and densely populated counties. In Brazil, the VL urbanization is a challenge for the control program. The goals were to identify the greater risk areas for human VL and the risk factors involved in transmission.
This is an ecological study on the relative risk of human VL. Spatial units of analysis were the coverage areas of the Basic Health Units (146 small-areas) of Belo Horizonte, Minas Gerais State, Brazil. Human VL cases, from 2007 to 2009 (n = 412), were obtained in the Brazilian Reportable Disease Information System. Bayesian approach was used to model the relative risk of VL including potential risk factors involved in transmission (canine infection, socioeconomic and environmental features) and to identify the small-areas of greater risk to human VL.
The relative risk of VL was shown to be correlated with income, education, and the number of infected dogs per inhabitants. The estimates of relative risk of VL were higher than 1.0 in 54% of the areas (79/146). The spatial modeling highlighted 14 areas with the highest relative risk of VL and 12 of them are concentrated in the northern region of the city.
The spatial analysis used in this study is useful for the identification of small-areas according to risk of human VL and presents operational applicability in control and surveillance program in an urban environment with an unequal spatial distribution of the disease. Thus the frequent monitoring of relative risk of human VL in small-areas is important to direct and prioritize the actions of the control program in urban environment, especially in big cities.</description><subject>Brazil - epidemiology</subject><subject>Disease transmission</subject><subject>Distribution</subject><subject>Dogs</subject><subject>Fatalities</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Infections</subject><subject>Information systems</subject><subject>Kala-azar</subject><subject>Leishmaniasis, Visceral - epidemiology</subject><subject>Leishmaniasis, Visceral - transmission</subject><subject>Medical geography</subject><subject>Parasitic diseases</subject><subject>Risk Factors</subject><subject>Socioeconomic factors</subject><subject>Studies</subject><subject>Urban Population</subject><issn>1935-2735</issn><issn>1935-2727</issn><issn>1935-2735</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>DOA</sourceid><recordid>eNptkl2L1DAYhYso7rr6D0QLgngzY_Lmo6kXwrr4sbAg-HEd3qbpTMZMMybtwPrrTZ3uMgPSi5TkOScnh7conlOypKyibzdhjD365a4f2iUhBAQnD4pzWjOxgIqJh0f_Z8WTlDaEiFoo-rg4Aw6cV5U8L75_sx4Ht7dldOlXGbpy75KxEX3prUvrLfYOk0ul68sPEf84_67EMu2yJiOYA9zOp2NssC8xWnxaPOrQJ_tsXi-Kn58-_rj6srj5-vn66vJmYSTUwwJbAVRVtawNtLyhrWwUbahppFCWccAWLIdO5aQMiDJESsyamiHLMBB2Ubw8-O58SHruI2nKpRJK1BIycX0g2oAbvYtui_FWB3T630aIK41xcMZbLbhSFYHOVGy6kDcAlbHGCEtYndvKXu_n28Zma1tj-yG3dGJ6etK7tV6FvWYKSCWnuG9mgxh-jzYNejtV7T32NoxT7hpyZgCZ0VcHdIU5muu7kB3NhOtLJkAJIiTN1PI_VP5au3Um9LZzef9E8PpIsLboh3UKfhxc6NMpyA-giSGlaLv7Z1Kip-m7a1tP06fn6cuyF8cV3Yvuxo39BS481VY</recordid><startdate>20131101</startdate><enddate>20131101</enddate><creator>de Araújo, Valdelaine Etelvina Miranda</creator><creator>Pinheiro, Letícia Cavalari</creator><creator>Almeida, Maria Cristina de Mattos</creator><creator>de Menezes, Fernanda Carvalho</creator><creator>Morais, Maria Helena Franco</creator><creator>Reis, Ilka Afonso</creator><creator>Assunção, Renato Martins</creator><creator>Carneiro, Mariângela</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U1</scope><scope>7U2</scope><scope>C1K</scope><scope>F1W</scope><scope>H95</scope><scope>H97</scope><scope>L.G</scope><scope>M7N</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20131101</creationdate><title>Relative risk of visceral leishmaniasis in Brazil: a spatial analysis in urban area</title><author>de Araújo, Valdelaine Etelvina Miranda ; Pinheiro, Letícia Cavalari ; Almeida, Maria Cristina de Mattos ; de Menezes, Fernanda Carvalho ; Morais, Maria Helena Franco ; Reis, Ilka Afonso ; Assunção, Renato Martins ; Carneiro, Mariângela</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c629t-ad52187969c2d4b1d6b81b1cb658e342ad2e42f84473208c066aad593a3b1d203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Brazil - epidemiology</topic><topic>Disease transmission</topic><topic>Distribution</topic><topic>Dogs</topic><topic>Fatalities</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Infections</topic><topic>Information systems</topic><topic>Kala-azar</topic><topic>Leishmaniasis, Visceral - epidemiology</topic><topic>Leishmaniasis, Visceral - transmission</topic><topic>Medical geography</topic><topic>Parasitic diseases</topic><topic>Risk Factors</topic><topic>Socioeconomic factors</topic><topic>Studies</topic><topic>Urban Population</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Araújo, Valdelaine Etelvina Miranda</creatorcontrib><creatorcontrib>Pinheiro, Letícia Cavalari</creatorcontrib><creatorcontrib>Almeida, Maria Cristina de Mattos</creatorcontrib><creatorcontrib>de Menezes, Fernanda Carvalho</creatorcontrib><creatorcontrib>Morais, Maria Helena Franco</creatorcontrib><creatorcontrib>Reis, Ilka Afonso</creatorcontrib><creatorcontrib>Assunção, Renato Martins</creatorcontrib><creatorcontrib>Carneiro, Mariângela</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PLoS neglected tropical diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Araújo, Valdelaine Etelvina Miranda</au><au>Pinheiro, Letícia Cavalari</au><au>Almeida, Maria Cristina de Mattos</au><au>de Menezes, Fernanda Carvalho</au><au>Morais, Maria Helena Franco</au><au>Reis, Ilka Afonso</au><au>Assunção, Renato Martins</au><au>Carneiro, Mariângela</au><au>Kamhawi, Shaden</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relative risk of visceral leishmaniasis in Brazil: a spatial analysis in urban area</atitle><jtitle>PLoS neglected tropical diseases</jtitle><addtitle>PLoS Negl Trop Dis</addtitle><date>2013-11-01</date><risdate>2013</risdate><volume>7</volume><issue>11</issue><spage>e2540</spage><pages>e2540-</pages><issn>1935-2735</issn><issn>1935-2727</issn><eissn>1935-2735</eissn><abstract>Visceral leishmaniasis (VL) is a vector-borne disease whose factors involved in transmission are poorly understood, especially in more urban and densely populated counties. In Brazil, the VL urbanization is a challenge for the control program. The goals were to identify the greater risk areas for human VL and the risk factors involved in transmission.
This is an ecological study on the relative risk of human VL. Spatial units of analysis were the coverage areas of the Basic Health Units (146 small-areas) of Belo Horizonte, Minas Gerais State, Brazil. Human VL cases, from 2007 to 2009 (n = 412), were obtained in the Brazilian Reportable Disease Information System. Bayesian approach was used to model the relative risk of VL including potential risk factors involved in transmission (canine infection, socioeconomic and environmental features) and to identify the small-areas of greater risk to human VL.
The relative risk of VL was shown to be correlated with income, education, and the number of infected dogs per inhabitants. The estimates of relative risk of VL were higher than 1.0 in 54% of the areas (79/146). The spatial modeling highlighted 14 areas with the highest relative risk of VL and 12 of them are concentrated in the northern region of the city.
The spatial analysis used in this study is useful for the identification of small-areas according to risk of human VL and presents operational applicability in control and surveillance program in an urban environment with an unequal spatial distribution of the disease. Thus the frequent monitoring of relative risk of human VL in small-areas is important to direct and prioritize the actions of the control program in urban environment, especially in big cities.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>24244776</pmid><doi>10.1371/journal.pntd.0002540</doi><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1935-2735 |
ispartof | PLoS neglected tropical diseases, 2013-11, Vol.7 (11), p.e2540 |
issn | 1935-2735 1935-2727 1935-2735 |
language | eng |
recordid | cdi_plos_journals_1468585962 |
source | MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central Open Access; Public Library of Science (PLoS); EZB-FREE-00999 freely available EZB journals; PubMed Central |
subjects | Brazil - epidemiology Disease transmission Distribution Dogs Fatalities Health aspects Humans Infections Information systems Kala-azar Leishmaniasis, Visceral - epidemiology Leishmaniasis, Visceral - transmission Medical geography Parasitic diseases Risk Factors Socioeconomic factors Studies Urban Population |
title | Relative risk of visceral leishmaniasis in Brazil: a spatial analysis in urban area |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T01%3A42%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relative%20risk%20of%20visceral%20leishmaniasis%20in%20Brazil:%20a%20spatial%20analysis%20in%20urban%20area&rft.jtitle=PLoS%20neglected%20tropical%20diseases&rft.au=de%20Ara%C3%BAjo,%20Valdelaine%20Etelvina%20Miranda&rft.date=2013-11-01&rft.volume=7&rft.issue=11&rft.spage=e2540&rft.pages=e2540-&rft.issn=1935-2735&rft.eissn=1935-2735&rft_id=info:doi/10.1371/journal.pntd.0002540&rft_dat=%3Cgale_plos_%3EA352850561%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1492623226&rft_id=info:pmid/24244776&rft_galeid=A352850561&rft_doaj_id=oai_doaj_org_article_5488702fc7344734b227cecc5e039244&rfr_iscdi=true |