Prevalence and predictors of antibiotic administration during pregnancy and birth
Antibiotic treatment during pregnancy and birth is very common. In this study, we describe the estimated prevalence of antibiotic administration during pregnancy and birth in the COPSAC2010 pregnancy cohort, and analyze dependence on social and lifestyle-related factors. 706 pregnant women from the...
Gespeichert in:
| Veröffentlicht in: | PloS one 2013-12, Vol.8 (12), p.e82932-e82932 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e82932 |
|---|---|
| container_issue | 12 |
| container_start_page | e82932 |
| container_title | PloS one |
| container_volume | 8 |
| creator | Stokholm, Jakob Schjørring, Susanne Pedersen, Louise Bischoff, Anne Louise Følsgaard, Nilofar Carson, Charlotte G Chawes, Bo L K Bønnelykke, Klaus Mølgaard, Anne Krogfelt, Karen A Bisgaard, Hans |
| description | Antibiotic treatment during pregnancy and birth is very common. In this study, we describe the estimated prevalence of antibiotic administration during pregnancy and birth in the COPSAC2010 pregnancy cohort, and analyze dependence on social and lifestyle-related factors.
706 pregnant women from the novel unselected Copenhagen Prospective Study on Asthma in Childhood (COPSAC2010) pregnancy cohort participated in this analysis. Detailed information on oral antibiotic prescriptions during pregnancy filled at the pharmacy was obtained and verified longitudinally. Information on intrapartum antibiotics, social, and lifestyle-factors was obtained by personal interviews.
The prevalence of antibiotic use was 37% during pregnancy and 33% intrapartum. Lower maternal age at birth; adjusted odds ratio (aOR) 0.94, 95% CI, [0.90-0.98], p = 0.003 and maternal smoking; aOR 1.97, 95% CI, [1.07-3.63], p = 0.030 were associated with use of antibiotics for urinary tract infection during pregnancy. Maternal educational level (low vs. high), aOR 2.32, 95% CI, [1.24-4.35], p = 0.011, maternal asthma; aOR 1.99, 95% CI, [1.33-2.98], p < 0.001 and previous childbirth; aOR 1.80, 95% CI, [1.21-2.66], p = 0.004 were associated with use of antibiotics for respiratory tract infection during pregnancy. Lower gestational age; aOR 0.72, 95% CI, [0.61-0.85], p < 0.001, maternal smoking; aOR 2.84, 95% CI, [1.33-6.06], p = 0.007, and nulliparity; aOR 1.79, 95% CI, [1.06-3.02], p = 0.030 were associated with administration of intrapartum antibiotics in women giving birth vaginally.
Antibiotic administration during pregnancy and birth may be influenced by social and lifestyle-factors. Understanding such risk factors may guide preventive strategies in order to avoid unnecessary use of antibiotics. |
| doi_str_mv | 10.1371/journal.pone.0082932 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1466546185</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A478345543</galeid><doaj_id>oai_doaj_org_article_9cc6d60fe2d5486f9642c2e1967e56d1</doaj_id><sourcerecordid>A478345543</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-cc56cc0f2ed0deefabe8a6fbfdcd092cc25ea48bf688533dff86d2c1cca53213</originalsourceid><addsrcrecordid>eNqNkl1r2zAUhs3YWLts_2BsgcHYLpLpw1Lkm0Ep-wgUuo-yWyFLR46KI2WSXdZ_PzlxSzx6MXQhcfy877GO3qJ4idES0xX-cB366FW73AUPS4QEqSh5VJzivC04QfTx0fmkeJbSNUKMCs6fFiekpCVCXJwW379FuFEteA1z5c18F8E43YWY5sHmSudqFzqn58psnXepi6pzwc9NH51vBrzxyuvbvbh2sds8L55Y1SZ4Me6z4urzp6vzr4uLyy_r87OLheYV6RZaM641sgQMMgBW1SAUt7U12qCKaE0YqFLUlgvBKDXWCm6IxlorRgmms-L1wXbXhiTHYSSJS85ZyXHWzIr1gTBBXctddFsVb2VQTu4LITZSxXy1FmSlNTccWSCGlYLbipdEE8AVXwHjZuj2cezW11swGnweRDsxnX7xbiObcCOpYIKiKhu8Gw1i-N1D6uTWJQ1tqzyEfv_fFcFstRp6vfkHffh2I9Xk15PO25D76sFUnpUrQUvGSpqp5QNUXga2TufkWJfrE8H7iSAzHfzpGtWnJNc_f_w_e_lryr49Yjeg2m6TQtsPYUpTsDyAOoaUItj7IWMkh-DfTUMOwZdj8LPs1fED3Yvukk7_Ansb_9E</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1466546185</pqid></control><display><type>article</type><title>Prevalence and predictors of antibiotic administration during pregnancy and birth</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Public Library of Science (PLoS) Journals Open Access</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Stokholm, Jakob ; Schjørring, Susanne ; Pedersen, Louise ; Bischoff, Anne Louise ; Følsgaard, Nilofar ; Carson, Charlotte G ; Chawes, Bo L K ; Bønnelykke, Klaus ; Mølgaard, Anne ; Krogfelt, Karen A ; Bisgaard, Hans</creator><contributor>Thorne, Claire</contributor><creatorcontrib>Stokholm, Jakob ; Schjørring, Susanne ; Pedersen, Louise ; Bischoff, Anne Louise ; Følsgaard, Nilofar ; Carson, Charlotte G ; Chawes, Bo L K ; Bønnelykke, Klaus ; Mølgaard, Anne ; Krogfelt, Karen A ; Bisgaard, Hans ; Thorne, Claire</creatorcontrib><description>Antibiotic treatment during pregnancy and birth is very common. In this study, we describe the estimated prevalence of antibiotic administration during pregnancy and birth in the COPSAC2010 pregnancy cohort, and analyze dependence on social and lifestyle-related factors.
706 pregnant women from the novel unselected Copenhagen Prospective Study on Asthma in Childhood (COPSAC2010) pregnancy cohort participated in this analysis. Detailed information on oral antibiotic prescriptions during pregnancy filled at the pharmacy was obtained and verified longitudinally. Information on intrapartum antibiotics, social, and lifestyle-factors was obtained by personal interviews.
The prevalence of antibiotic use was 37% during pregnancy and 33% intrapartum. Lower maternal age at birth; adjusted odds ratio (aOR) 0.94, 95% CI, [0.90-0.98], p = 0.003 and maternal smoking; aOR 1.97, 95% CI, [1.07-3.63], p = 0.030 were associated with use of antibiotics for urinary tract infection during pregnancy. Maternal educational level (low vs. high), aOR 2.32, 95% CI, [1.24-4.35], p = 0.011, maternal asthma; aOR 1.99, 95% CI, [1.33-2.98], p < 0.001 and previous childbirth; aOR 1.80, 95% CI, [1.21-2.66], p = 0.004 were associated with use of antibiotics for respiratory tract infection during pregnancy. Lower gestational age; aOR 0.72, 95% CI, [0.61-0.85], p < 0.001, maternal smoking; aOR 2.84, 95% CI, [1.33-6.06], p = 0.007, and nulliparity; aOR 1.79, 95% CI, [1.06-3.02], p = 0.030 were associated with administration of intrapartum antibiotics in women giving birth vaginally.
Antibiotic administration during pregnancy and birth may be influenced by social and lifestyle-factors. Understanding such risk factors may guide preventive strategies in order to avoid unnecessary use of antibiotics.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0082932</identifier><identifier>PMID: 24340068</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Administration, Oral ; Adult ; Alcohol use ; Analysis ; Anti-Bacterial Agents - administration & dosage ; Antibiotics ; Asthma ; Birth ; Cesarean section ; Childbirth & labor ; Childhood asthma ; Children ; Cohort Studies ; Delivery (Childbirth) ; Denmark ; Drug Therapy - statistics & numerical data ; Drugstores ; Female ; Gestational age ; Health sciences ; Hospitals ; Humans ; Infections ; Life Style ; Maternal Age ; Odds Ratio ; Parturition ; Pharmacy ; Pregnancy ; Pregnancy Complications, Infectious - drug therapy ; Pregnancy Complications, Infectious - epidemiology ; Pregnant women ; Prescription drugs ; Prevalence ; Respiratory tract ; Respiratory tract diseases ; Risk analysis ; Risk Factors ; Smoking ; Studies ; Surveillance ; Urinary tract ; Urinary tract diseases ; Urinary tract infections ; Urogenital system ; Womens health</subject><ispartof>PloS one, 2013-12, Vol.8 (12), p.e82932-e82932</ispartof><rights>COPYRIGHT 2013 Public Library of Science</rights><rights>2013 Stokholm et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2013 Stokholm et al 2013 Stokholm et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-cc56cc0f2ed0deefabe8a6fbfdcd092cc25ea48bf688533dff86d2c1cca53213</citedby><cites>FETCH-LOGICAL-c692t-cc56cc0f2ed0deefabe8a6fbfdcd092cc25ea48bf688533dff86d2c1cca53213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858309/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858309/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2929,23871,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24340068$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Thorne, Claire</contributor><creatorcontrib>Stokholm, Jakob</creatorcontrib><creatorcontrib>Schjørring, Susanne</creatorcontrib><creatorcontrib>Pedersen, Louise</creatorcontrib><creatorcontrib>Bischoff, Anne Louise</creatorcontrib><creatorcontrib>Følsgaard, Nilofar</creatorcontrib><creatorcontrib>Carson, Charlotte G</creatorcontrib><creatorcontrib>Chawes, Bo L K</creatorcontrib><creatorcontrib>Bønnelykke, Klaus</creatorcontrib><creatorcontrib>Mølgaard, Anne</creatorcontrib><creatorcontrib>Krogfelt, Karen A</creatorcontrib><creatorcontrib>Bisgaard, Hans</creatorcontrib><title>Prevalence and predictors of antibiotic administration during pregnancy and birth</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Antibiotic treatment during pregnancy and birth is very common. In this study, we describe the estimated prevalence of antibiotic administration during pregnancy and birth in the COPSAC2010 pregnancy cohort, and analyze dependence on social and lifestyle-related factors.
706 pregnant women from the novel unselected Copenhagen Prospective Study on Asthma in Childhood (COPSAC2010) pregnancy cohort participated in this analysis. Detailed information on oral antibiotic prescriptions during pregnancy filled at the pharmacy was obtained and verified longitudinally. Information on intrapartum antibiotics, social, and lifestyle-factors was obtained by personal interviews.
The prevalence of antibiotic use was 37% during pregnancy and 33% intrapartum. Lower maternal age at birth; adjusted odds ratio (aOR) 0.94, 95% CI, [0.90-0.98], p = 0.003 and maternal smoking; aOR 1.97, 95% CI, [1.07-3.63], p = 0.030 were associated with use of antibiotics for urinary tract infection during pregnancy. Maternal educational level (low vs. high), aOR 2.32, 95% CI, [1.24-4.35], p = 0.011, maternal asthma; aOR 1.99, 95% CI, [1.33-2.98], p < 0.001 and previous childbirth; aOR 1.80, 95% CI, [1.21-2.66], p = 0.004 were associated with use of antibiotics for respiratory tract infection during pregnancy. Lower gestational age; aOR 0.72, 95% CI, [0.61-0.85], p < 0.001, maternal smoking; aOR 2.84, 95% CI, [1.33-6.06], p = 0.007, and nulliparity; aOR 1.79, 95% CI, [1.06-3.02], p = 0.030 were associated with administration of intrapartum antibiotics in women giving birth vaginally.
Antibiotic administration during pregnancy and birth may be influenced by social and lifestyle-factors. Understanding such risk factors may guide preventive strategies in order to avoid unnecessary use of antibiotics.</description><subject>Administration, Oral</subject><subject>Adult</subject><subject>Alcohol use</subject><subject>Analysis</subject><subject>Anti-Bacterial Agents - administration & dosage</subject><subject>Antibiotics</subject><subject>Asthma</subject><subject>Birth</subject><subject>Cesarean section</subject><subject>Childbirth & labor</subject><subject>Childhood asthma</subject><subject>Children</subject><subject>Cohort Studies</subject><subject>Delivery (Childbirth)</subject><subject>Denmark</subject><subject>Drug Therapy - statistics & numerical data</subject><subject>Drugstores</subject><subject>Female</subject><subject>Gestational age</subject><subject>Health sciences</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infections</subject><subject>Life Style</subject><subject>Maternal Age</subject><subject>Odds Ratio</subject><subject>Parturition</subject><subject>Pharmacy</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - drug therapy</subject><subject>Pregnancy Complications, Infectious - epidemiology</subject><subject>Pregnant women</subject><subject>Prescription drugs</subject><subject>Prevalence</subject><subject>Respiratory tract</subject><subject>Respiratory tract diseases</subject><subject>Risk analysis</subject><subject>Risk Factors</subject><subject>Smoking</subject><subject>Studies</subject><subject>Surveillance</subject><subject>Urinary tract</subject><subject>Urinary tract diseases</subject><subject>Urinary tract infections</subject><subject>Urogenital system</subject><subject>Womens health</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNkl1r2zAUhs3YWLts_2BsgcHYLpLpw1Lkm0Ep-wgUuo-yWyFLR46KI2WSXdZ_PzlxSzx6MXQhcfy877GO3qJ4idES0xX-cB366FW73AUPS4QEqSh5VJzivC04QfTx0fmkeJbSNUKMCs6fFiekpCVCXJwW379FuFEteA1z5c18F8E43YWY5sHmSudqFzqn58psnXepi6pzwc9NH51vBrzxyuvbvbh2sds8L55Y1SZ4Me6z4urzp6vzr4uLyy_r87OLheYV6RZaM641sgQMMgBW1SAUt7U12qCKaE0YqFLUlgvBKDXWCm6IxlorRgmms-L1wXbXhiTHYSSJS85ZyXHWzIr1gTBBXctddFsVb2VQTu4LITZSxXy1FmSlNTccWSCGlYLbipdEE8AVXwHjZuj2cezW11swGnweRDsxnX7xbiObcCOpYIKiKhu8Gw1i-N1D6uTWJQ1tqzyEfv_fFcFstRp6vfkHffh2I9Xk15PO25D76sFUnpUrQUvGSpqp5QNUXga2TufkWJfrE8H7iSAzHfzpGtWnJNc_f_w_e_lryr49Yjeg2m6TQtsPYUpTsDyAOoaUItj7IWMkh-DfTUMOwZdj8LPs1fED3Yvukk7_Ansb_9E</recordid><startdate>20131210</startdate><enddate>20131210</enddate><creator>Stokholm, Jakob</creator><creator>Schjørring, Susanne</creator><creator>Pedersen, Louise</creator><creator>Bischoff, Anne Louise</creator><creator>Følsgaard, Nilofar</creator><creator>Carson, Charlotte G</creator><creator>Chawes, Bo L K</creator><creator>Bønnelykke, Klaus</creator><creator>Mølgaard, Anne</creator><creator>Krogfelt, Karen A</creator><creator>Bisgaard, Hans</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20131210</creationdate><title>Prevalence and predictors of antibiotic administration during pregnancy and birth</title><author>Stokholm, Jakob ; Schjørring, Susanne ; Pedersen, Louise ; Bischoff, Anne Louise ; Følsgaard, Nilofar ; Carson, Charlotte G ; Chawes, Bo L K ; Bønnelykke, Klaus ; Mølgaard, Anne ; Krogfelt, Karen A ; Bisgaard, Hans</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-cc56cc0f2ed0deefabe8a6fbfdcd092cc25ea48bf688533dff86d2c1cca53213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Administration, Oral</topic><topic>Adult</topic><topic>Alcohol use</topic><topic>Analysis</topic><topic>Anti-Bacterial Agents - administration & dosage</topic><topic>Antibiotics</topic><topic>Asthma</topic><topic>Birth</topic><topic>Cesarean section</topic><topic>Childbirth & labor</topic><topic>Childhood asthma</topic><topic>Children</topic><topic>Cohort Studies</topic><topic>Delivery (Childbirth)</topic><topic>Denmark</topic><topic>Drug Therapy - statistics & numerical data</topic><topic>Drugstores</topic><topic>Female</topic><topic>Gestational age</topic><topic>Health sciences</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infections</topic><topic>Life Style</topic><topic>Maternal Age</topic><topic>Odds Ratio</topic><topic>Parturition</topic><topic>Pharmacy</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Infectious - drug therapy</topic><topic>Pregnancy Complications, Infectious - epidemiology</topic><topic>Pregnant women</topic><topic>Prescription drugs</topic><topic>Prevalence</topic><topic>Respiratory tract</topic><topic>Respiratory tract diseases</topic><topic>Risk analysis</topic><topic>Risk Factors</topic><topic>Smoking</topic><topic>Studies</topic><topic>Surveillance</topic><topic>Urinary tract</topic><topic>Urinary tract diseases</topic><topic>Urinary tract infections</topic><topic>Urogenital system</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stokholm, Jakob</creatorcontrib><creatorcontrib>Schjørring, Susanne</creatorcontrib><creatorcontrib>Pedersen, Louise</creatorcontrib><creatorcontrib>Bischoff, Anne Louise</creatorcontrib><creatorcontrib>Følsgaard, Nilofar</creatorcontrib><creatorcontrib>Carson, Charlotte G</creatorcontrib><creatorcontrib>Chawes, Bo L K</creatorcontrib><creatorcontrib>Bønnelykke, Klaus</creatorcontrib><creatorcontrib>Mølgaard, Anne</creatorcontrib><creatorcontrib>Krogfelt, Karen A</creatorcontrib><creatorcontrib>Bisgaard, Hans</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stokholm, Jakob</au><au>Schjørring, Susanne</au><au>Pedersen, Louise</au><au>Bischoff, Anne Louise</au><au>Følsgaard, Nilofar</au><au>Carson, Charlotte G</au><au>Chawes, Bo L K</au><au>Bønnelykke, Klaus</au><au>Mølgaard, Anne</au><au>Krogfelt, Karen A</au><au>Bisgaard, Hans</au><au>Thorne, Claire</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence and predictors of antibiotic administration during pregnancy and birth</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2013-12-10</date><risdate>2013</risdate><volume>8</volume><issue>12</issue><spage>e82932</spage><epage>e82932</epage><pages>e82932-e82932</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Antibiotic treatment during pregnancy and birth is very common. In this study, we describe the estimated prevalence of antibiotic administration during pregnancy and birth in the COPSAC2010 pregnancy cohort, and analyze dependence on social and lifestyle-related factors.
706 pregnant women from the novel unselected Copenhagen Prospective Study on Asthma in Childhood (COPSAC2010) pregnancy cohort participated in this analysis. Detailed information on oral antibiotic prescriptions during pregnancy filled at the pharmacy was obtained and verified longitudinally. Information on intrapartum antibiotics, social, and lifestyle-factors was obtained by personal interviews.
The prevalence of antibiotic use was 37% during pregnancy and 33% intrapartum. Lower maternal age at birth; adjusted odds ratio (aOR) 0.94, 95% CI, [0.90-0.98], p = 0.003 and maternal smoking; aOR 1.97, 95% CI, [1.07-3.63], p = 0.030 were associated with use of antibiotics for urinary tract infection during pregnancy. Maternal educational level (low vs. high), aOR 2.32, 95% CI, [1.24-4.35], p = 0.011, maternal asthma; aOR 1.99, 95% CI, [1.33-2.98], p < 0.001 and previous childbirth; aOR 1.80, 95% CI, [1.21-2.66], p = 0.004 were associated with use of antibiotics for respiratory tract infection during pregnancy. Lower gestational age; aOR 0.72, 95% CI, [0.61-0.85], p < 0.001, maternal smoking; aOR 2.84, 95% CI, [1.33-6.06], p = 0.007, and nulliparity; aOR 1.79, 95% CI, [1.06-3.02], p = 0.030 were associated with administration of intrapartum antibiotics in women giving birth vaginally.
Antibiotic administration during pregnancy and birth may be influenced by social and lifestyle-factors. Understanding such risk factors may guide preventive strategies in order to avoid unnecessary use of antibiotics.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>24340068</pmid><doi>10.1371/journal.pone.0082932</doi><tpages>e82932</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2013-12, Vol.8 (12), p.e82932-e82932 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1466546185 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Public Library of Science (PLoS) Journals Open Access; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Administration, Oral Adult Alcohol use Analysis Anti-Bacterial Agents - administration & dosage Antibiotics Asthma Birth Cesarean section Childbirth & labor Childhood asthma Children Cohort Studies Delivery (Childbirth) Denmark Drug Therapy - statistics & numerical data Drugstores Female Gestational age Health sciences Hospitals Humans Infections Life Style Maternal Age Odds Ratio Parturition Pharmacy Pregnancy Pregnancy Complications, Infectious - drug therapy Pregnancy Complications, Infectious - epidemiology Pregnant women Prescription drugs Prevalence Respiratory tract Respiratory tract diseases Risk analysis Risk Factors Smoking Studies Surveillance Urinary tract Urinary tract diseases Urinary tract infections Urogenital system Womens health |
| title | Prevalence and predictors of antibiotic administration during pregnancy and birth |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-14T11%3A56%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20and%20predictors%20of%20antibiotic%20administration%20during%20pregnancy%20and%20birth&rft.jtitle=PloS%20one&rft.au=Stokholm,%20Jakob&rft.date=2013-12-10&rft.volume=8&rft.issue=12&rft.spage=e82932&rft.epage=e82932&rft.pages=e82932-e82932&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0082932&rft_dat=%3Cgale_plos_%3EA478345543%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1466546185&rft_id=info:pmid/24340068&rft_galeid=A478345543&rft_doaj_id=oai_doaj_org_article_9cc6d60fe2d5486f9642c2e1967e56d1&rfr_iscdi=true |