Alpha-actinin is a new type of house dust mite allergen

Main indoor allergens for humans are from house dust mites. There are more than 30 allergens in Dermatophagoides farinae but only fourteen allergens have been identified from this mite including Der f 1-3, 6, 7, 10, 11, 13-18, and 22. A native allergen protein (Der f 24, 90 kDa) was purified from D....

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Veröffentlicht in:	PloS one 2013-12, Vol.8 (12), p.e81377-e81377
Hauptverfasser:	An, Su, Shen, Chuanbing, Liu, Xiaoyu, Chen, Lingling, Xu, Xuemei, Rong, Mingqiang, Liu, Zhigang, Lai, Ren
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinin - chemistry Actinin - immunology Actinin - isolation & purification Adolescent Adult Allergenicity Allergens Allergens - chemistry Allergens - immunology Allergens - isolation & purification Allergies Allergy Amino Acid Sequence Animals Antigens, Dermatophagoides - chemistry Antigens, Dermatophagoides - immunology Antigens, Dermatophagoides - isolation & purification Base Sequence Basophils - immunology CD63 antigen Cell Extracts Chromatography Cloning Der f 1 antigen Dermatophagoides farinae Disease DNA, Complementary - genetics Dust Edman degradation EF-hand Electrophoresis, Gel, Two-Dimensional Enzyme-linked immunosorbent assay Enzymes Gel filtration Histamine House dust Humans Hypersensitivity Immunoblotting Immunoglobulin E Immunoglobulin E - blood Immunoglobulin E - metabolism Immunology Indoor air pollution Laboratories Leukocytes (basophilic) Liquid chromatography Mass spectrometry Mass spectroscopy Middle Aged Mites Molecular Sequence Data Molecular Weight Patients Proteins Pyroglyphidae - immunology Skin Skin Tests Spectrometry, Mass, Electrospray Ionization Studies Surface active agents Young Adult Zoology α-Actinin
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