The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults
The prevalence of type 2 diabetes within the Republic of Ireland is poorly defined, although a recent report suggested 135,000 cases in adults aged 45+, with approximately one-third of these undiagnosed. This study aims to assess the prevalence of undiagnosed and diagnosed diabetes in middle-aged ad...
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| description | The prevalence of type 2 diabetes within the Republic of Ireland is poorly defined, although a recent report suggested 135,000 cases in adults aged 45+, with approximately one-third of these undiagnosed. This study aims to assess the prevalence of undiagnosed and diagnosed diabetes in middle-aged adults, and compare features related to either condition, in order to investigate why certain individuals remain undetected.
This was a cross-sectional study involving a sample of 2,047 men and women, aged between 50-69 years, randomly selected from a large primary care centre. Univariate logistic regression was used to explore socio-economic, metabolic and other health related variable associations with undiagnosed or diagnosed diabetes. A final multivariate analysis was used to determine odds ratios and 95% confidence intervals for having undiagnosed compared to diagnosed diabetes, adjusted for gender, age and significant covariates determined from univariate models.
The total prevalence of diabetes was 8.5% (95% CI: 7.4%-8.8%); 72 subjects (3.5%) had undiagnosed diabetes (95% CI: 2.8%-4.4%) and 102 subjects (5.0%) had diagnosed diabetes (95% CI: 4.1%-6.0%). Obesity, dyslipidaemia, and family history of diabetes were positively associated with both undiagnosed and diagnosed type 2 diabetes. Compared with diagnosed subjects, study participants with undiagnosed diabetes were significantly more likely to have low levels of physical activity and were less likely to be on treatment for diabetes-related conditions or to have private medical insurance.
The prevalence of diabetes within the Cork and Kerry Diabetes and Heart Disease Study is comparable to recent estimates from the Slán National Health and Lifestyle Survey, a study which was nationally representative of the general population. A considerable proportion of diabetes cases were undiagnosed (41%), emphasising the need for more effective detection strategies and equitable access to primary healthcare. |
| doi_str_mv | 10.1371/journal.pone.0080504 |
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This was a cross-sectional study involving a sample of 2,047 men and women, aged between 50-69 years, randomly selected from a large primary care centre. Univariate logistic regression was used to explore socio-economic, metabolic and other health related variable associations with undiagnosed or diagnosed diabetes. A final multivariate analysis was used to determine odds ratios and 95% confidence intervals for having undiagnosed compared to diagnosed diabetes, adjusted for gender, age and significant covariates determined from univariate models.
The total prevalence of diabetes was 8.5% (95% CI: 7.4%-8.8%); 72 subjects (3.5%) had undiagnosed diabetes (95% CI: 2.8%-4.4%) and 102 subjects (5.0%) had diagnosed diabetes (95% CI: 4.1%-6.0%). Obesity, dyslipidaemia, and family history of diabetes were positively associated with both undiagnosed and diagnosed type 2 diabetes. Compared with diagnosed subjects, study participants with undiagnosed diabetes were significantly more likely to have low levels of physical activity and were less likely to be on treatment for diabetes-related conditions or to have private medical insurance.
The prevalence of diabetes within the Cork and Kerry Diabetes and Heart Disease Study is comparable to recent estimates from the Slán National Health and Lifestyle Survey, a study which was nationally representative of the general population. A considerable proportion of diabetes cases were undiagnosed (41%), emphasising the need for more effective detection strategies and equitable access to primary healthcare.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0080504</identifier><identifier>PMID: 24282548</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adults ; Agreements ; Biochemistry ; Blood Glucose - analysis ; Blood pressure ; Chronic illnesses ; Chronology ; Confidence intervals ; Coronary artery disease ; Cross-Sectional Studies ; Diabetes ; Diabetes mellitus ; Diabetes Mellitus, Type 2 - epidemiology ; Dyslipidemia ; Epidemiology ; Exercise ; Female ; Genetics ; Glucose ; Glycated Hemoglobin - analysis ; Health care ; Health care access ; Heart ; Heart diseases ; Hemoglobin ; Humans ; Hyperglycemia ; Hypertension ; Ireland - epidemiology ; Laboratories ; Lifestyles ; Male ; Medical records ; Middle Aged ; Multivariate analysis ; Nutrition ; Obesity ; Physical activity ; Population ; Prevalence ; Primary care ; Public health ; Regression analysis ; Statistical analysis ; Studies ; Systematic review ; Womens health</subject><ispartof>PloS one, 2013-11, Vol.8 (11), p.e80504</ispartof><rights>2013 O Connor et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/3.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2013 O Connor et al 2013 O Connor et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c526t-5ddf17aaae62be5002e8ca39a62066e9f9dfc336d9359a3acebcaca006c2d223</citedby><cites>FETCH-LOGICAL-c526t-5ddf17aaae62be5002e8ca39a62066e9f9dfc336d9359a3acebcaca006c2d223</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840064/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840064/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2929,23871,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24282548$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Dasgupta, Kaberi</contributor><creatorcontrib>O Connor, Jennifer M</creatorcontrib><creatorcontrib>Millar, Seán R</creatorcontrib><creatorcontrib>Buckley, Claire M</creatorcontrib><creatorcontrib>Kearney, Patricia M</creatorcontrib><creatorcontrib>Perry, Ivan J</creatorcontrib><title>The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The prevalence of type 2 diabetes within the Republic of Ireland is poorly defined, although a recent report suggested 135,000 cases in adults aged 45+, with approximately one-third of these undiagnosed. This study aims to assess the prevalence of undiagnosed and diagnosed diabetes in middle-aged adults, and compare features related to either condition, in order to investigate why certain individuals remain undetected.
This was a cross-sectional study involving a sample of 2,047 men and women, aged between 50-69 years, randomly selected from a large primary care centre. Univariate logistic regression was used to explore socio-economic, metabolic and other health related variable associations with undiagnosed or diagnosed diabetes. A final multivariate analysis was used to determine odds ratios and 95% confidence intervals for having undiagnosed compared to diagnosed diabetes, adjusted for gender, age and significant covariates determined from univariate models.
The total prevalence of diabetes was 8.5% (95% CI: 7.4%-8.8%); 72 subjects (3.5%) had undiagnosed diabetes (95% CI: 2.8%-4.4%) and 102 subjects (5.0%) had diagnosed diabetes (95% CI: 4.1%-6.0%). Obesity, dyslipidaemia, and family history of diabetes were positively associated with both undiagnosed and diagnosed type 2 diabetes. Compared with diagnosed subjects, study participants with undiagnosed diabetes were significantly more likely to have low levels of physical activity and were less likely to be on treatment for diabetes-related conditions or to have private medical insurance.
The prevalence of diabetes within the Cork and Kerry Diabetes and Heart Disease Study is comparable to recent estimates from the Slán National Health and Lifestyle Survey, a study which was nationally representative of the general population. A considerable proportion of diabetes cases were undiagnosed (41%), emphasising the need for more effective detection strategies and equitable access to primary healthcare.</description><subject>Adults</subject><subject>Agreements</subject><subject>Biochemistry</subject><subject>Blood Glucose - analysis</subject><subject>Blood pressure</subject><subject>Chronic illnesses</subject><subject>Chronology</subject><subject>Confidence intervals</subject><subject>Coronary artery disease</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Dyslipidemia</subject><subject>Epidemiology</subject><subject>Exercise</subject><subject>Female</subject><subject>Genetics</subject><subject>Glucose</subject><subject>Glycated Hemoglobin - analysis</subject><subject>Health care</subject><subject>Health care access</subject><subject>Heart</subject><subject>Heart diseases</subject><subject>Hemoglobin</subject><subject>Humans</subject><subject>Hyperglycemia</subject><subject>Hypertension</subject><subject>Ireland - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>O Connor, Jennifer M</au><au>Millar, Seán R</au><au>Buckley, Claire M</au><au>Kearney, Patricia M</au><au>Perry, Ivan J</au><au>Dasgupta, Kaberi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2013-11-25</date><risdate>2013</risdate><volume>8</volume><issue>11</issue><spage>e80504</spage><pages>e80504-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The prevalence of type 2 diabetes within the Republic of Ireland is poorly defined, although a recent report suggested 135,000 cases in adults aged 45+, with approximately one-third of these undiagnosed. This study aims to assess the prevalence of undiagnosed and diagnosed diabetes in middle-aged adults, and compare features related to either condition, in order to investigate why certain individuals remain undetected.
This was a cross-sectional study involving a sample of 2,047 men and women, aged between 50-69 years, randomly selected from a large primary care centre. Univariate logistic regression was used to explore socio-economic, metabolic and other health related variable associations with undiagnosed or diagnosed diabetes. A final multivariate analysis was used to determine odds ratios and 95% confidence intervals for having undiagnosed compared to diagnosed diabetes, adjusted for gender, age and significant covariates determined from univariate models.
The total prevalence of diabetes was 8.5% (95% CI: 7.4%-8.8%); 72 subjects (3.5%) had undiagnosed diabetes (95% CI: 2.8%-4.4%) and 102 subjects (5.0%) had diagnosed diabetes (95% CI: 4.1%-6.0%). Obesity, dyslipidaemia, and family history of diabetes were positively associated with both undiagnosed and diagnosed type 2 diabetes. Compared with diagnosed subjects, study participants with undiagnosed diabetes were significantly more likely to have low levels of physical activity and were less likely to be on treatment for diabetes-related conditions or to have private medical insurance.
The prevalence of diabetes within the Cork and Kerry Diabetes and Heart Disease Study is comparable to recent estimates from the Slán National Health and Lifestyle Survey, a study which was nationally representative of the general population. A considerable proportion of diabetes cases were undiagnosed (41%), emphasising the need for more effective detection strategies and equitable access to primary healthcare.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>24282548</pmid><doi>10.1371/journal.pone.0080504</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Adults Agreements Biochemistry Blood Glucose - analysis Blood pressure Chronic illnesses Chronology Confidence intervals Coronary artery disease Cross-Sectional Studies Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - epidemiology Dyslipidemia Epidemiology Exercise Female Genetics Glucose Glycated Hemoglobin - analysis Health care Health care access Heart Heart diseases Hemoglobin Humans Hyperglycemia Hypertension Ireland - epidemiology Laboratories Lifestyles Male Medical records Middle Aged Multivariate analysis Nutrition Obesity Physical activity Population Prevalence Primary care Public health Regression analysis Statistical analysis Studies Systematic review Womens health |
| title | The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults |
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