The role of TLR4 896 A>G and 1196 C>T in susceptibility to infections: a review and meta-analysis of genetic association studies

Toll-like receptor 4 plays a role in pathogen recognition, and common polymorphisms may alter host susceptibility to infectious diseases. To review the association of two common polymorphisms (TLR4 896A>G and TLR4 1196C>T) with infectious diseases. We searched PubMed and EMBASE up to March 201...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e81047-e81047
Hauptverfasser:	Ziakas, Panayiotis D, Prodromou, Michael L, El Khoury, Joseph, Zintzaras, Elias, Mylonakis, Eleftherios
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Brucellosis Cutaneous leishmaniasis Cysticercosis Data processing Fever Genes Genetic Predisposition to Disease Genome-Wide Association Study Gum disease Health risks Hospitals Humans Immunology Infection - genetics Infections Infectious diseases Inflammation Inflammatory response Leprosy Lists Malaria Medical schools Meta-analysis Mutation Parasitic diseases Polymorphism, Genetic Populations Porphyromonas gingivalis Pregnancy Proteins Streptococcus infections Studies TLR4 protein Toll-Like Receptor 4 - genetics Toll-like receptors Tonsil Tuberculosis Typhoid Urinary tract Vaginosis Vector-borne diseases Waterborne diseases
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