Cytokines and tumor metastasis gene variants in oral cancer and precancer in Puerto Rico

A cross-sectional epidemiological study explored genetic susceptibility to oral precancer and cancer in Puerto Rico (PR). Three hundred three individuals with a benign oral condition, oral precancer (oral epithelial hyperplasia/hyperkeratosis, oral epithelial dysplasia), or oral squamous cell carcin...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e79187-e79187
Hauptverfasser:	Erdei, Esther, Luo, Li, Sheng, Huiping, Maestas, Erika, White, Kirsten A M, Mackey, Amanda, Dong, Yan, Berwick, Marianne, Morse, Douglas E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alcohol use Alcohols Alleles Analysis Benign Biomedical laboratories Cancer Cancer genetics Cancer metastasis Cancer research Cytokines Dental materials Disease prevention Diseases Dysplasia Epidemiology Female Gene Frequency - genetics Genes Genetic analysis Genetic aspects Genetic Predisposition to Disease - genetics Genotype Genotyping Health sciences Hispanic people Humans Hyperplasia Immune system Interleukin-10 - genetics Interleukin-1beta - genetics Internal medicine Interstitial collagenase Laboratories Logistic Models Male Matrix metalloproteinase Medical diagnosis Medical research Medicine Metalloproteinase Metastases Metastasis Middle Aged Mouth Mucosa - metabolism Mouth Mucosa - pathology Mouth Neoplasms - genetics Mouth Neoplasms - metabolism Oral cancer Oral squamous cell carcinoma Polymorphism Polymorphism, Single Nucleotide - genetics Puerto Rico Regression analysis Single nucleotide polymorphisms Single-nucleotide polymorphism Smoking Squamous cell carcinoma Throat cancer TNF inhibitors Transforming growth factors Tumor necrosis factor-TNF Tumor necrosis factor-α
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