Methylome analysis and epigenetic changes associated with menarcheal age

Reproductive factors have been linked to both breast cancer and DNA methylation, suggesting methylation as an important mechanism by which reproductive factors impact on disease risk. However, few studies have investigated the link between reproductive factors and DNA methylation in humans. Genome-w...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e79391-e79391
Hauptverfasser:	Demetriou, Christiana A, Chen, Jia, Polidoro, Silvia, van Veldhoven, Karin, Cuenin, Cyrille, Campanella, Gianluca, Brennan, Kevin, Clavel-Chapelon, Françoise, Dossus, Laure, Kvaskoff, Marina, Drogan, Dagmar, Boeing, Heiner, Kaaks, Rudolf, Risch, Angela, Trichopoulos, Dimitrios, Lagiou, Pagona, Masala, Giovanna, Sieri, Sabina, Tumino, Rosario, Panico, Salvatore, Quirós, J Ramón, Sánchez Perez, María-José, Amiano, Pilar, Huerta Castaño, José María, Ardanaz, Eva, Onland-Moret, Charlotte, Peeters, Petra, Khaw, Kay-Tee, Wareham, Nick, Key, Timothy J, Travis, Ruth C, Romieu, Isabelle, Gallo, Valentina, Gunter, Marc, Herceg, Zdenko, Kyriacou, Kyriacos, Riboli, Elio, Flanagan, James M, Vineis, Paolo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Alcohol use Analysis Body measurements Breast cancer Cancer genetics Cell cycle Chronic illnesses Clinical medicine CpG islands CpG Islands - genetics Deoxyribonucleic acid DNA DNA methylation DNA Methylation - genetics Epidemiology Epigenesis, Genetic - genetics Epigenetic inheritance Epigenetics Female Genetics Genomes Genomics Health care Health risks Health sciences Hormones Humans Loci Lymphocytes Medical research Menarche Menarche - genetics Menarche - physiology Methylation Microscopy Middle Aged Mutation Nutrition Peripheral blood Population Preventive medicine Primary care Prospective Studies Public health Regression analysis Risk analysis Risk factors Women's health
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