Links between the oncoprotein YB-1 and small non-coding RNAs in breast cancer

The nucleic acid-binding protein YB-1, a member of the cold-shock domain protein family, has been implicated in the progression of breast cancer and is associated with poor patient survival. YB-1 has sequence similarity to LIN28, another cold-shock protein family member, which has a role in the regu...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e80171-e80171
Hauptverfasser:	Blenkiron, Cherie, Hurley, Daniel G, Fitzgerald, Sandra, Print, Cristin G, Lasham, Annette
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Acids Antibodies Bioinformatics Biosynthesis Biotechnology Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Cancer Cell growth Cell Line, Tumor Cold shock Cold shock proteins Development and progression Female Gene expression Genomes Humans Hypotheses Immunoprecipitation Kinases Machinery Machinery and equipment MCF-7 Cells Medicine MicroRNA MicroRNAs miRNA Nucleoli Oncogene Proteins - genetics Oncogene Proteins - metabolism Oncoproteins Pathology Protein binding Proteins Ribonucleic acid RNA RNA, Messenger - genetics RNA, Small Untranslated - genetics RNA, Small Untranslated - metabolism Shock snoRNA Stem cells Studies Transfer RNA tRNA Tumor cell lines Y-Box-Binding Protein 1 - genetics Y-Box-Binding Protein 1 - metabolism
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