Functionalized carbon nanotubes in the brain: cellular internalization and neuroinflammatory responses

The potential use of functionalized carbon nanotubes (f-CNTs) for drug and gene delivery to the central nervous system (CNS) and as neural substrates makes the understanding of their in vivo interactions with the neural tissue essential. The aim of this study was to investigate the interactions betw...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e80964
Hauptverfasser:	Bardi, Giuseppe, Nunes, Antonio, Gherardini, Lisa, Bates, Katie, Al-Jamal, Khuloud T, Gaillard, Claire, Prato, Maurizio, Bianco, Alberto, Pizzorusso, Tommaso, Kostarelos, Kostas
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonia Animals Astrocytes Astrocytes - drug effects Astrocytes - metabolism Astrocytes - pathology Biological Transport Biomarkers - metabolism Brain Brain - drug effects Brain - metabolism Brain - pathology Carbon CD11b antigen CD11b Antigen - genetics CD11b Antigen - metabolism Cell activation Central nervous system Chemical Sciences Cortex Cytokines Cytokines - genetics Cytokines - metabolism Disease Drug delivery systems Female Gene Expression Gene transfer Glial cells Glial Fibrillary Acidic Protein Immunohistochemistry In vivo methods and tests Inflammation Inflammation - chemically induced Inflammation - metabolism Inflammation - pathology Injections, Intraventricular Internalization Laboratories Localization Medical imaging Medicinal Chemistry Mice Mice, Inbred C57BL Microglia Microglia - drug effects Microglia - metabolism Microglia - pathology Multi wall carbon nanotubes Nanotechnology Nanotubes Nanotubes, Carbon - chemistry Nanotubes, Carbon - toxicity Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neurons - drug effects Neurons - metabolism Neurons - pathology Neurophysiology Neurosciences Overexpression Oxidation Oxidation-Reduction Pharmacy Physiology Stereotaxic Techniques Studies Substrates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!