Loss of the TGF[beta]-Activating Integrin [alpha]v[beta]8 on Dendritic Cells Protects Mice from Chronic Intestinal Parasitic Infection via Control of Type 2 Immunity

  Chronic intestinal parasite infection is a major global health problem, but mechanisms that promote chronicity are poorly understood. Here we describe a novel cellular and molecular pathway involved in the development of chronic intestinal parasite infection. We show that, early during development...

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Veröffentlicht in:	PLoS pathogens 2013-10, Vol.9 (10)
Hauptverfasser:	Worthington, John, Klementowicz, Joanna, Rahman, Sayema, Czajkowska, Beata, Catherine Smedley, Waldmann, Herman, Sparwasser, Tim, Grencis, Richard, Travis, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Immune system Infections Parasites T cell receptors
Online-Zugang:	Volltext
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