Human cytomegalovirus latency-associated proteins elicit immune-suppressive IL-10 producing CD4⁺ T cells

Human cytomegalovirus (HCMV) is a widely prevalent human herpesvirus, which, after primary infection, persists in the host for life. In healthy individuals, the virus is well controlled by the HCMV-specific T cell response. A key feature of this persistence, in the face of a normally robust host imm...

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Veröffentlicht in:PLoS pathogens 2013-10, Vol.9 (10), p.e1003635-e1003635
Hauptverfasser: Mason, Gavin M, Jackson, Sarah, Okecha, Georgina, Poole, Emma, Sissons, J G Patrick, Sinclair, John, Wills, Mark R
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Sprache:eng
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