Gatifloxacin versus ofloxacin for the treatment of uncomplicated enteric fever in Nepal: an open-label, randomized, controlled trial

Fluoroquinolones are the most commonly used group of antimicrobials for the treatment of enteric fever, but no direct comparison between two fluoroquinolones has been performed in a large randomised trial. An open-label randomized trial was conducted to investigate whether gatifloxacin is more effec...

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Veröffentlicht in:	PLoS neglected tropical diseases 2013-10, Vol.7 (10), p.e2523-e2523
Hauptverfasser:	Koirala, Samir, Basnyat, Buddha, Arjyal, Amit, Shilpakar, Olita, Shrestha, Kabina, Shrestha, Rishav, Shrestha, Upendra Man, Agrawal, Krishna, Koirala, Kanika Deshpande, Thapa, Sudeep Dhoj, Karkey, Abhilasha, Dongol, Sabina, Giri, Abhishek, Shakya, Mila, Pathak, Kamal Raj, Campbell, James, Baker, Stephen, Farrar, Jeremy, Wolbers, Marcel, Dolecek, Christiane
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Adolescent Anti-Bacterial Agents - administration & dosage Child Comparative analysis Developing countries Drug dosages Drug resistance in microorganisms Drug Resistance, Bacterial Drug therapy Female Fever Fluoroquinolones - administration & dosage Gatifloxacin Health facilities Humans LDCs Male Mutation Nepal Ofloxacin Ofloxacin - administration & dosage Salmonella Salmonella paratyphi A - drug effects Salmonella paratyphi A - isolation & purification Salmonella typhi - drug effects Salmonella typhi - isolation & purification Testing Treatment Failure Tropical diseases Typhoid fever Typhoid Fever - drug therapy Young Adult
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