Effect of artificial selection on runs of homozygosity in u.s. Holstein cattle

The intensive selection programs for milk made possible by mass artificial insemination increased the similarity among the genomes of North American (NA) Holsteins tremendously since the 1960s. This migration of elite alleles has caused certain regions of the genome to have runs of homozygosity (ROH...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e80813-e80813
Hauptverfasser:	Kim, Eui-Soo, Cole, John B, Huson, Heather, Wiggans, George R, Van Tassell, Curtis P, Crooker, Brian A, Liu, George, Da, Yang, Sonstegard, Tad S
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis animal breeding Animal sciences Animals Artificial insemination artificial selection Base pairs Bovidae Breeding Cattle Chromosomes genome Genomes Genomics Haplotypes Holstein Homozygosity Homozygote Inbreeding inbreeding coefficient Laboratories loci Migration Milk milk fat yield Milk production milk protein yield Population Quantitative genetics Quantitative trait loci Reproduction (biology) Schizophrenia Signatures United States Zoology
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