Annexin A4 is involved in proliferation, chemo-resistance and migration and invasion in ovarian clear cell adenocarcinoma cells

Ovarian clear cell adenocarcinoma (CCC) is the second most common subtype of ovarian cancer after high-grade serous adenocarcinomas. CCC tends to develop resistance to the standard platinum-based chemotherapy, and has a poor prognosis when diagnosed in advanced stages. The ANXA4 gene, along with its...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e80359-e80359
Hauptverfasser:	Mogami, Tae, Yokota, Naho, Asai-Sato, Mikiko, Yamada, Roppei, Koizume, Shiro, Sakuma, Yuji, Yoshihara, Mitsuyo, Nakamura, Yoshiyasu, Takano, Yasuo, Hirahara, Fumiki, Miyagi, Yohei, Miyagi, Etsuko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma, Clear Cell - genetics Adenocarcinoma, Clear Cell - metabolism Adenocarcinoma, Clear Cell - pathology Annexin A4 - genetics Annexin A4 - metabolism Binding sites Biotechnology Blotting, Western Breast cancer Calcium Cancer Carboplatin Cell division Cell growth Cell Line, Tumor Cell migration Cell Movement - genetics Cell Movement - physiology Cell proliferation Cell Proliferation - physiology Chemoresistance Chemotherapy Diagnosis Drug Resistance, Neoplasm - physiology Extracellular Matrix Proteins - genetics Extracellular Matrix Proteins - metabolism Female Gastric cancer Gene expression Genetics Growth factors Growth rate Gynecology Humans Hyaluronan Receptors - genetics Hyaluronan Receptors - metabolism Isoelectric Point Isoelectric points Kinases Lysosomal-Associated Membrane Protein 2 - genetics Lysosomal-Associated Membrane Protein 2 - metabolism Medicine Mutation Obstetrics Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Pancreatic cancer Pathology Platinum Prognosis Protein binding Proteins Proteomics Stomach cancer University graduates
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