Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype

Epidemiological studies have shown that low plasma levels of high-density lipoprotein (HDL) cholesterol are associated with increased risk of cardiovascular disease, but the mechanisms for the possible atheroprotective effects of HDL cholesterol have still not been fully clarified, in particular in...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e78241-e78241
Hauptverfasser:	Holven, Kirsten B, Retterstøl, Kjetil, Ueland, Thor, Ulven, Stine M, Nenseter, Marit S, Sandvik, Marit, Narverud, Ingunn, Berge, Knut E, Ose, Leiv, Aukrust, Pål, Halvorsen, Bente
Format:	Artikel
Sprache:	eng
Schlagworte:	ABCA1 protein Adiponectin Adult Aged Arteriosclerosis Atherosclerosis Atherosclerosis - blood Atherosclerotic disorders ATP Binding Cassette Transporter 1 - blood ATP Binding Cassette Transporter, Sub-Family G, Member 1 ATP-Binding Cassette Transporters - blood ATP-binding protein Biological Transport, Active Blood cholesterol C-Reactive Protein - metabolism Cardiovascular disease Cardiovascular diseases Chemokine CXCL16 Chemokines, CXC - blood Cholesterol Cholesterol Levels Cholesterol, HDL - blood CXCL16 protein Efflux Epidemiological studies Epidemiology Female Females Gelatinase B Gene expression Genetic aspects Health risks High density lipoprotein Humans Inflammation Inflammation - blood Intercellular adhesion molecule 1 Intercellular Adhesion Molecule-1 - blood Kar- og thoraxkirurgi: 782 Kardiologi: 771 Klinisk medisinske fag: 750 Leukocytes (mononuclear) Lipoproteins (high density) Lipoproteins (low density) Lipoproteins, LDL - blood Low density lipoprotein Low density lipoproteins Male Males Matrix Metalloproteinase 9 - blood Medisinske Fag: 700 Middle Aged Mortality Neopterin Neopterin - blood Oxidation-Reduction Paraoxonase Peripheral blood mononuclear cells Phenotype Phenotypes Plasma Plasma levels Receptors, Scavenger - blood RNA Sex VDP
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