Dynein associates with oskar mRNPs and is required for their efficient net plus-end localization in Drosophila oocytes

In order for eukaryotic cells to function properly, they must establish polarity. The Drosophila oocyte uses mRNA localization to establish polarity and hence provides a genetically tractable model in which to study this process. The spatial restriction of oskar mRNA and its subsequent protein produ...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e80605-e80605
Hauptverfasser:	Sanghavi, Paulomi, Laxani, Shobha, Li, Xuan, Bullock, Simon L, Gonsalvez, Graydon B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell division Cellular biology Chains Drosophila Drosophila Proteins - genetics Drosophila Proteins - metabolism Dynein Dyneins - genetics Dyneins - metabolism Embryogenesis Embryos Female Hypotheses Immunoprecipitation Insects Kinesin Laboratories Localization Medical research Messenger RNA Microtubules Molecular biology Motility mRNA Mutants Myosin Oocytes Oocytes - metabolism Pattern formation Polarity Proteins Ribonucleoproteins - genetics Ribonucleoproteins - metabolism
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