Copy number variation of Fc gamma receptor genes in HIV-infected and HIV-tuberculosis co-infected individuals in sub-Saharan Africa

AIDS, caused by the retrovirus HIV, remains the largest cause of morbidity in sub-Saharan Africa yet almost all genetic studies have focused on cohorts from Western countries. HIV shows high co-morbidity with tuberculosis (TB), as HIV stimulates the reactivation of latent tuberculosis (TB). Recent c...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e78165-e78165
Hauptverfasser:	Machado, Lee R, Bowdrey, Jennifer, Ngaimisi, Eliford, Habtewold, Abiy, Minzi, Omary, Makonnen, Eyasu, Yimer, Getnet, Amogne, Wondwossen, Mugusi, Sabina, Janabi, Mohammed, Aderaye, Getachew, Mugusi, Ferdinand, Viskaduraki, Maria, Aklillu, Eleni, Hollox, Edward J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Activation Africa South of the Sahara AIDS Analysis Antibodies Antibodies - genetics Antibodies - immunology Antiretroviral agents Antiretroviral drugs B cells Clinical trials Coinfection - genetics Coinfection - immunology Coinfection - pathology Copy number Disease DNA Copy Number Variations - genetics Fc receptors Female Gene expression Genes Genetic diversity Genetic research Genetic variance Genetics GPI-Linked Proteins - genetics GPI-Linked Proteins - immunology Highly active antiretroviral therapy HIV HIV - immunology HIV - pathogenicity HIV infections HIV Infections - genetics HIV Infections - immunology HIV Infections - pathology HIV patients Human immunodeficiency virus Humans Immunoglobulin G Immunoglobulins Infections Infektionsmedicin Internal medicine Klinisk medicin Laboratories Male Medical research Medicin och hälsovetenskap Medicine Medicinsk genetik Medicinska och farmaceutiska grundvetenskaper Morbidity Mycobacterium tuberculosis Neutrophils Pharmacology Pharmacy Receptors Receptors, IgG - genetics Receptors, IgG - immunology Tuberculosis Tuberculosis - genetics Tuberculosis - immunology Tuberculosis - pathology
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