CDK-dependent nuclear localization of B-cyclin Clb1 promotes FEAR activation during meiosis I in budding yeast

Cyclin-dependent kinases (CDK) are master regulators of the cell cycle in eukaryotes. CDK activity is regulated by the presence, post-translational modification and spatial localization of its regulatory subunit cyclin. In budding yeast, the B-cyclin Clb1 is phosphorylated and localizes to the nucle...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11), p.e79001-e79001
Hauptverfasser:	Tibbles, Katherine Louise, Sarkar, Sourav, Novak, Bela, Arumugam, Prakash
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Anaphase Baking yeast Biochemistry Blotting, Western Cell culture Cell cycle Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell division Cell Nucleus - metabolism Chromosomes Cyclin B - genetics Cyclin B - metabolism Cyclin-dependent kinase Cyclin-Dependent Kinases - genetics Cyclin-Dependent Kinases - metabolism Deoxyribonucleic acid DNA Eukaryotes Fear Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Kinases Localization Meiosis Metaphase Nuclei Phosphatase Phosphorylation Phosphotransferases Polo-like kinase Post-translation Protein Tyrosine Phosphatases - genetics Protein Tyrosine Phosphatases - metabolism Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Proteins Regulators Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Signal Transduction Spatial discrimination Yeast
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