Differences in visceral fat and fat bacterial colonization between ulcerative colitis and Crohn's disease. An in vivo and in vitro study

Crohn's disease (CD) is notably characterized by the expansion of visceral fat with small adipocytes expressing a high proportion of anti-inflammatory genes. Conversely, visceral fat depots in ulcerative colitis (UC) patients have never been characterized. Our study aims were a) to compare adip...

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Veröffentlicht in:	PloS one 2013-10, Vol.8 (10), p.e78495-e78495
Hauptverfasser:	Zulian, Alessandra, Cancello, Raffaella, Ruocco, Chiara, Gentilini, Davide, Di Blasio, Anna Maria, Danelli, Piergiorgio, Micheletto, Giancarlo, Cesana, Elisabetta, Invitti, Cecilia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipocytes - metabolism Adipose tissue Adipose Tissue - metabolism Adipose Tissue - microbiology Angiogenesis Apoptosis Bacteria Bacterial diseases Bacterial infections Bacterial Translocation - physiology Cadmium Cell Proliferation - genetics Chemotaxis Colitis, Ulcerative - genetics Colitis, Ulcerative - metabolism Colitis, Ulcerative - microbiology Colonization Crohn Disease - genetics Crohn Disease - metabolism Crohn Disease - microbiology Crohn's disease Crohns disease Diabetes DNA microarrays Down-Regulation - genetics Enterococcus faecalis - metabolism Experiments Gene expression Genes Gram-Positive Bacterial Infections - genetics Gram-Positive Bacterial Infections - metabolism Gram-Positive Bacterial Infections - microbiology Humans In vivo methods and tests Infections Inflammation - embryology Inflammation - genetics Inflammation - microbiology Inflammatory bowel disease Inflammatory bowel diseases Intestine Intra-Abdominal Fat - metabolism Laboratories Laser microscopy Light microscopy Medical research Metallothioneins Microbiota Molecular biology Morphology Patients Preadipocytes Proteins Rodents Systematic review Transcriptome - genetics Translocation Ulcerative colitis Up-Regulation - genetics
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