Can K-ras gene mutation be utilized as prognostic biomarker for colorectal cancer patients receiving chemotherapy? A meta-analysis and systematic review

K-ras gene mutations were common in colorectal patients, but their relationship with prognosis was unclear. Verify prognostic differences between patient with and without mutant K-ras genes by reviewing the published evidence. Systematic reviews and data bases were searched for cohort/case-control s...

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Veröffentlicht in:PloS one 2013-10, Vol.8 (10), p.e77901
Hauptverfasser: Rui, Yuan-Yi, Zhang, Dan, Zhou, Zong-Guang, Wang, Cun, Yang, Lie, Yu, Yong-Yang, Chen, Hai-Ning
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Sprache:eng
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