The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster

The coordination of cell proliferation and differentiation is crucial for proper development. In particular, robust mechanisms exist to ensure that cells permanently exit the cell cycle upon terminal differentiation, and these include restraining the activities of both the E2F/DP transcription facto...

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Veröffentlicht in:PLoS genetics 2013-09, Vol.9 (9), p.e1003835
Hauptverfasser: Bandura, Jennifer L, Jiang, Huaqi, Nickerson, Derek W, Edgar, Bruce A
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Sprache:eng
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