Changes of cytokines during a spaceflight analog--a 45-day head-down bed rest

Spaceflight is associated with deregulation in the immune system. Head-down bed rest (HDBR) at -6° is believed to be the most practical model for examining multi-system responses to microgravity in humans during spaceflight. In the present study, a 45-day HDBR was performed to investigate the altera...

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Veröffentlicht in:	PloS one 2013-10, Vol.8 (10), p.e77401-e77401
Hauptverfasser:	Xu, Xi, Tan, Cheng, Li, Pingping, Zhang, Shusong, Pang, Xuewen, Liu, Hongju, Li, Li, Sun, Xiuyuan, Zhang, Yu, Wu, Hounan, Chen, Xiaoping, Ge, Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aerospace medicine Analysis Arthritis Astronauts B cells Bed Rest Cytokines Cytokines - biosynthesis Cytokines - blood Deregulation Gene expression Glucocorticoids Head Headspace Health sciences Humans Hydrocortisone Immobilization Immune system Immunity Immunoglobulins Immunological memory Immunology Immunoregulation Immunotherapy Inflammation Interferon Interleukin Interleukin 1 Interleukin 17 Interleukin 18 Interleukins Laboratories Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - metabolism Lymphocytes Lymphocytes B Lymphocytes T Male Medicine Memory Memory cells Microgravity Myeloid cells Plant Extracts - pharmacology Rhodiola - chemistry Rhodiola rosea Space Flight T cells Weightlessness Simulation - methods γ-Interferon
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