Volatile emissions from Mycobacterium avium subsp. paratuberculosis mirror bacterial growth and enable distinction of different strains

Control of paratuberculosis in livestock is hampered by the low sensitivity of established direct and indirect diagnostic methods. Like other bacteria, Mycobacterium avium subsp. paratuberculosis (MAP) emits volatile organic compounds (VOCs). Differences of VOC patterns in breath and feces of infect...

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Veröffentlicht in:	PloS one 2013-10, Vol.8 (10), p.e76868-e76868
Hauptverfasser:	Trefz, Phillip, Koehler, Heike, Klepik, Klaus, Moebius, Petra, Reinhold, Petra, Schubert, Jochen K, Miekisch, Wolfram
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Aldehydes - analysis Animal experimentation Animals Bacteria Bioindicators Biomarkers Cattle Culture media Culture Media, Conditioned - analysis Culture Media, Conditioned - chemistry Cytokines Deer Density Diagnostic systems Dilution Disease Emission Emissions Esters Ethyl acetate Feces Feces - microbiology Fibers Furans - analysis Gas Chromatography-Mass Spectrometry - methods Growth Headspace Hydrocarbons - analysis Intensive care Johne's disease Laboratories Livestock Mycobacterium avium Mycobacterium avium subsp. paratuberculosis - classification Mycobacterium avium subsp. paratuberculosis - genetics Mycobacterium avium subsp. paratuberculosis - metabolism Mycobacterium tuberculosis Organic compounds Paratuberculosis Paratuberculosis - diagnosis Paratuberculosis - microbiology Pasteurization Pollution control Principal Component Analysis Sensitivity and Specificity Sheep Solid phase methods Species Specificity Strains (organisms) VOCs Volatile compounds Volatile organic compounds Volatile Organic Compounds - analysis Volatiles
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