Genetic characteristics of the human hepatic stellate cell line LX-2

The human hepatic cell line LX-2 has been described as tool to study mechanisms of hepatic fibrogenesis and the testing of antifibrotic compounds. It was originally generated by immortalisation with the Simian Vacuolating Virus 40 (SV40) transforming (T) antigen and subsequent propagation in low ser...

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Veröffentlicht in:	PloS one 2013-10, Vol.8 (10), p.e75692-e75692
Hauptverfasser:	Weiskirchen, Ralf, Weimer, Jörg, Meurer, Steffen K, Kron, Anja, Seipel, Barbara, Vater, Inga, Arnold, Norbert, Siebert, Reiner, Xu, Lieming, Friedman, Scott L, Bergmann, Carsten
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Biology Cancer Cell culture Cell Line Chromosomes Extracellular matrix Genetics Genotypes Growth factors Gynecology Hepatic Stellate Cells - cytology Hepatic Stellate Cells - metabolism Hepatology Humans Karyotype Karyotyping Laboratories Liver Liver diseases Medical research Metabolism Molecular chains Obstetrics Proteins Rodents Viruses
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