Comparative immunogenicity of 7 and 13-valent pneumococcal conjugate vaccines and the development of functional antibodies to cross-reactive serotypes

Protection against disease or colonization from serotypes related to those in pneumococcal conjugate vaccines (i.e. cross-protection) vary by serotype; the basis for this variation is not understood. The 13-valent pneumococcal conjugate vaccine (PCV13) replaced 7-valent conjugate (PCV7) in the USA i...

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Veröffentlicht in:	PloS one 2013-09, Vol.8 (9), p.e74906-e74906
Hauptverfasser:	Grant, Lindsay R, O'Brien, Sarah E, Burbidge, Polly, Haston, Mitch, Zancolli, Marta, Cowell, Lucy, Johnson, Marina, Weatherholtz, Robert C, Reid, Raymond, Santosham, Mathuram, O'Brien, Katherine L, Goldblatt, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Bacterial - immunology Child Children Children & youth Childrens health Colonization Comparative analysis Cross Reactions - immunology Cross-protection Disease control Ear diseases Enzyme-linked immunosorbent assay Female Health disparities Heptavalent Pneumococcal Conjugate Vaccine Humans Immunization Immunogenicity Immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - immunology Immunoglobulins In vitro methods and tests Infant Male Medical research Native Americans Native North Americans Pneumococcal Vaccines - immunology Public health Serotypes Serotyping Streptococcus infections Streptococcus pneumoniae Streptococcus pneumoniae - classification Streptococcus pneumoniae - immunology Studies Vaccines Vaccines, Conjugate - immunology
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