Sex- and subtype-specific analysis of H2AFX polymorphisms in non-Hodgkin lymphoma

H2AFX encodes a histone variant involved in signaling sites of DNA damage and recruiting repair factors. Genetic variants in H2AFX may influence risk of non-Hodgkin lymphoma (NHL), a heterogeneous group of lymphoid tumors that are characterized by chromosomal translocations. We previously reported t...

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Veröffentlicht in:	PLOS ONE 2013-09, Vol.8 (9), p.e74619-e74619
Hauptverfasser:	Bretherick, Karla L, Schuetz, Johanna M, Morton, Lindsay M, Purdue, Mark P, Conde, Lucia, Gallagher, Richard P, Connors, Joseph M, Gascoyne, Randy D, Berry, Brian R, Armstrong, Bruce, Kricker, Anne, Vajdic, Claire M, Grulich, Andrew, Hjalgrim, Henrik, Smedby, Karin E, Skibola, Christine F, Rothman, Nathaniel, Spinelli, John J, Brooks-Wilson, Angela R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Analysis B-cell lymphoma Binding sites Breast cancer Case-Control Studies Cell cycle Chromosome translocations Chromosomes Deoxyribonucleic acid DNA DNA damage DNA repair Endocrine therapy Environmental health Epidemiology Female Females Gene expression Genetic aspects Genetic diversity Genetic variance Genetics Genomes Genotype Haplotypes Health sciences Histones - genetics Humans Immunoglobulins Linkage Disequilibrium Lymphocytes B Lymphoma Lymphoma, Non-Hodgkin - diagnosis Lymphoma, Non-Hodgkin - genetics Male Mantle cell lymphoma Medical research Middle Aged Non-Hodgkin's lymphomas Pathology Phosphorylation Polymorphism, Single Nucleotide Population Population studies Public health Sex Sex Factors Signaling Single nucleotide polymorphisms Single-nucleotide polymorphism Tumors Young Adult
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