Systems-based approaches to probing metabolic variation within the Mycobacterium tuberculosis complex

The Mycobacterium tuberculosis complex includes bovine and human strains of the tuberculosis bacillus, including Mycobacterium tuberculosis, Mycobacterium bovis and the Mycobacterium bovis BCG vaccine strain. M. bovis has evolved from a M. tuberculosis-like ancestor and is the ancestor of the BCG va...

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Veröffentlicht in:	PloS one 2013-09, Vol.8 (9), p.e75913
Hauptverfasser:	Lofthouse, Emma K, Wheeler, Paul R, Beste, Dany J V, Khatri, Bhagwati L, Wu, Huihai, Mendum, Tom A, Kierzek, Andrzej M, McFadden, Johnjoe
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Analysis Antitubercular agents Bacillus Calmette-Guerin vaccine BCG Carbon Cattle Computer simulation Dehydrogenases Genetic aspects Genomes Genomics Glucose - pharmacokinetics Host range Investigations Laboratories Metabolic networks Metabolic Networks and Pathways - genetics Metabolic Networks and Pathways - physiology Metabolism Models, Biological Mycobacterium bovis Mycobacterium bovis - growth & development Mycobacterium bovis - metabolism Mycobacterium tuberculosis Mycobacterium tuberculosis - growth & development Mycobacterium tuberculosis - metabolism Networks Pathogenicity Pathogens Phenotype Physiological aspects Predictions Species Specificity Substrates Systems Biology - methods Tuberculosis Vaccines Virulence Virulence (Microbiology)
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