Adipose weight gain during chronic insulin treatment of mice results from changes in lipid storage without affecting de novo synthesis of palmitate

Insulin treatment is associated with increased adipose mass in both humans and mice. However, the underlying dynamic basis of insulin induced lipid accumulation in adipose tissue remains elusive. To assess this, young female C57BL6/J mice were fed a low fat diet for 3 weeks, treated subsequently wit...

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Veröffentlicht in:PloS one 2013-09, Vol.8 (9), p.e76060
Hauptverfasser: Frikke-Schmidt, Henriette, Pedersen, Thomas Åskov, Fledelius, Christian, Olsen, Grith Skytte, Hellerstein, Marc
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Sprache:eng
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