Cag type IV secretion system: CagI independent bacterial surface localization of CagA

Helicobacter pylori Cag type IV secretion system (Cag-T4SS) is a multi-component transporter of oncoprotein CagA across the bacterial membranes into the host epithelial cells. To understand the role of unique Cag-T4SS component CagI in CagA translocation, we have characterized it by biochemical and...

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Veröffentlicht in:	PloS one 2013-09, Vol.8 (9), p.e74620-e74620
Hauptverfasser:	Kumar, Navin, Shariq, Mohd, Kumari, Rajesh, Tyagi, Rakesh K, Mukhopadhyay, Gauranga
Format:	Artikel
Sprache:	eng
Schlagworte:	Agrobacterium tumefaciens Antigens, Bacterial - metabolism Bacteria Bacterial Proteins - metabolism Bacterial Secretion Systems Biosynthesis Cell surface Cloning, Molecular E coli Epithelial cells Escherichia coli Fimbriae, Bacterial - metabolism Genes Helicobacter pylori Helicobacter pylori - metabolism Infections Localization Medicine Membrane proteins Membrane Proteins - metabolism Membrane Transport Proteins - metabolism Membranes Mutation Pathogenesis Periplasm - metabolism Pili Plasmids - metabolism Polyamide-imides Protein Binding Protein transport Secretion Substrates Translocation Trinucleotide repeats
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