A small conductance calcium-activated K+ channel in C. elegans, KCNL-2, plays a role in the regulation of the rate of egg-laying

In the nervous system of mice, small conductance calcium-activated potassium (SK) channels function to regulate neuronal excitability through the generation of a component of the medium afterhyperpolarization that follows action potentials. In humans, irregular action potential firing frequency unde...

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Veröffentlicht in:	PloS one 2013-09, Vol.8 (9), p.e75869-e75869
Hauptverfasser:	Chotoo, Cavita K, Silverman, Gary A, Devor, Daniel C, Luke, Cliff J
Format:	Artikel
Sprache:	eng
Schlagworte:	Action potential Afterhyperpolarization Amino Acid Sequence Animals Ataxia Biology Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans - physiology Calcium Calcium channels Calcium conductance Calcium-binding protein Calmodulin Conductance Confocal Conserved Sequence Defects Developmental stages Egg laying Epilepsy Excitability Firing rate Fluorescence Fluoroscopic imaging Gene Expression Regulation Genetic engineering Hermaphrodites Homology Mammals Mental disorders Mice Molecular Sequence Data Nematodes Nervous system Nervous System - metabolism Neurological disorders Neurons Oviposition Pediatrics Phenotype Potassium Potassium channels Potassium conductance Protein Structure, Tertiary Resistance RNA polymerase Rodents Schizophrenia Small-Conductance Calcium-Activated Potassium Channels - chemistry Small-Conductance Calcium-Activated Potassium Channels - genetics Small-Conductance Calcium-Activated Potassium Channels - metabolism Transgenic Transmembrane domains Vulva Worms
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