The expression pattern of EVA1C, a novel Slit receptor, is consistent with an axon guidance role in the mouse nervous system

The Slit/Robo axon guidance families play a vital role in the formation of neural circuitry within select regions of the developing mouse nervous system. Typically Slits signal through the Robo receptors, however they also have Robo-independent functions. The novel Slit receptor Eva-1, recently disc...

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Veröffentlicht in:	PloS one 2013-09, Vol.8 (9), p.e74115-e74115
Hauptverfasser:	James, Gregory, Foster, Simon R, Key, Brian, Beverdam, Annemiek
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axon guidance Axons Axons - metabolism Cerebral Cortex - cytology Cerebral Cortex - metabolism Chromosome 21 Circuits Defects Down syndrome Down's syndrome Forebrain Gene Expression Heparan sulfate Hippocampus - cytology Hippocampus - metabolism Intellectual disabilities Mice Nervous system Nervous System - metabolism Neural circuitry Neural networks Olfactory Bulb - metabolism Receptors Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Retinal Ganglion Cells - metabolism Robo protein Science Selectivity Slit protein Slits Spinal cord Spinal Cord - metabolism Thalamus - cytology Thalamus - metabolism
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