Structure determination and biochemical characterization of a putative HNH endonuclease from Geobacter metallireducens GS-15

The crystal structure of a putative HNH endonuclease, Gmet_0936 protein from Geobacter metallireducens GS-15, has been determined at 2.6 Å resolution using single-wavelength anomalous dispersion method. The structure contains a two-stranded anti-parallel β-sheet that are surrounded by two helices on...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS One 2013-09, Vol.8 (9), p.e72114
Hauptverfasser:	Xu, Shuang-yong, Kuzin, Alexandre P, Seetharaman, Jayaraman, Gutjahr, Alice, Chan, Siu-Hong, Chen, Yang, Xiao, Rong, Acton, Thomas B, Montelione, Gaetano T, Tong, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Amino Acid Sequence Amino Acid Substitution Amino acids Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacteriology Binding sites Biochemistry Biotechnology Catalysis Catalytic Domain Cloning Consortia Crystal structure Crystallography Crystallography, X-Ray Deoxyribonucleic acid Dimerization Dimers DNA DNA Cleavage DNA repair DNA Repair Enzymes - chemistry DNA Repair Enzymes - genetics DNA-(Apurinic or Apyrimidinic Site) Lyase - chemistry DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics E coli Electrophoretic mobility Endonuclease Enzymes Genomics Geobacter Geobacter - enzymology Heat treatment Helices Homology Hydrogen-Ion Concentration Models, Molecular Molecular biology Molecular Sequence Data Mutagenesis, Site-Directed Nicking endonuclease Nucleases pH effects Phages Plasmids Polydeoxyribonucleotides - chemistry Protein Binding Protein expression Protein structure Protein Structure, Quaternary Protein Structure, Secondary Proteins Residues Secondary structure Sediments Structural analysis Substrate Specificity Substrates Zinc
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!