Down-regulation of SIX3 is associated with clinical outcome in lung adenocarcinoma

Lung cancer is a common cancer and the leading cause of cancer-related death worldwide. SIX3 is a human homologue of the highly conserved sine oculis gene family essential during embryonic development in vertebrates, and encodes a homeo-domain containing transcription factor. Little is known about t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-08, Vol.8 (8), p.e71816-e71816
Hauptverfasser:	Mo, Min-Li, Okamoto, Junichi, Chen, Zhao, Hirata, Tomomi, Mikami, Iwao, Bosco-Clément, Geneviève, Li, Hui, Zhou, Hai-Meng, Jablons, David M, He, Biao
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - metabolism Adenocarcinoma - mortality Adenocarcinoma - surgery Adenocarcinoma of Lung Aged Biology Biomarkers Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Cancer Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - surgery Cell growth Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Clinical outcomes Disease-Free Survival DNA Methylation DNA microarrays Down-Regulation Embryogenesis Embryonic development Embryonic growth stage Eye Proteins - genetics Eye Proteins - metabolism Female Gene expression Gene Expression Regulation, Neoplastic Genes Genes, Tumor Suppressor Genomics Hazards Homeobox Protein SIX3 Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Homology Humans Kaplan-Meier Estimate Life sciences Lung cancer Lung diseases Lung Neoplasms - metabolism Lung Neoplasms - mortality Lung Neoplasms - surgery Male Medical prognosis Medicine Metastases Methylation Middle Aged Multivariate Analysis Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Oligonucleotide Array Sequence Analysis Oncology Patient outcomes Patients Polymerase chain reaction Prognosis Promoter Regions, Genetic Proportional Hazards Models Proteins Regression analysis Regression models Restoration RNA Sine oculis gene Six3 gene Studies Surgery Survival Thoracic surgery Tissues Transcriptome Treatment Outcome Tumor cell lines Tumorigenesis Vertebrates Wound healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!