Electrical stimulation promotes wound healing by enhancing dermal fibroblast activity and promoting myofibroblast transdifferentiation

Electrical stimulation (ES) has long been used as an alternative clinical treatment and an effective approach to modulate cellular behaviours. In this work we investigated the effects of ES on human skin fibroblast activity, myofibroblast transdifferentiation and the consequence on wound healing. No...

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Veröffentlicht in:	PloS one 2013-08, Vol.8 (8), p.e71660-e71660
Hauptverfasser:	Rouabhia, Mahmoud, Park, Hyunjin, Meng, Shiyun, Derbali, Habib, Zhang, Ze
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actins - metabolism Anticoagulants Biology Breast cancer Cell adhesion & migration Cell culture Cell growth Cell Proliferation Cell Survival Cell Transdifferentiation Cells, Cultured Collagen Contraction Cytotoxicity Dentistry Dermis - cytology Dermis - physiology Diabetes Ecology Electric fields Electric properties Electric Stimulation Electrical stimuli Engineering Enzyme-Linked Immunosorbent Assay Exposure Extracellular matrix Fibroblast growth factor 1 Fibroblast Growth Factor 1 - metabolism Fibroblast growth factor 2 Fibroblast Growth Factor 2 - metabolism Fibroblasts Fibroblasts - cytology Fibroblasts - metabolism Genotype & phenotype Growth factors Heparin Humans Materials Science Membranes Microscopy, Fluorescence Muscle contraction Muscle, Smooth - chemistry Muscles Myofibroblasts - cytology Myofibroblasts - metabolism Physiology Polylactic acid Secretion Skin Smooth muscle Stimulation Surgery Time Factors Wound care Wound Healing
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