Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test

A multicenter study was conducted to evaluate the diagnostic accuracy (sensitivity and specificity) of the Verigene Gram-Positive Blood Culture Test (BC-GP) test to identify 12 Gram-positive bacterial gene targets and three genetic resistance determinants directly from positive blood culture broths...

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Veröffentlicht in:	PLoS medicine 2013-07, Vol.10 (7), p.e1001478
Hauptverfasser:	Buchan, Blake W, Ginocchio, Christine C, Manii, Ryhana, Cavagnolo, Robert, Pancholi, Preeti, Swyers, Lettie, Thomson, Jr, Richard B, Anderson, Christopher, Kaul, Karen, Ledeboer, Nathan A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Anti-Bacterial Agents - pharmacology Automation Bacillus Bacteria Bacterial infections Bacterial Proteins - genetics Bacterial Proteins - metabolism Biology Blood - microbiology Colony Count, Microbial - methods Confidence intervals Corynebacterium Drug Resistance, Bacterial - drug effects Enterococcus Enterococcus faecium Genes Genetic Markers - drug effects Gentian Violet - metabolism Gram-positive bacteria Gram-Positive Bacteria - classification Gram-Positive Bacteria - genetics Gram-Positive Bacteria - isolation & purification Host-parasite relationships Humans Immune system Listeria Medicine Methods Microarray Analysis - methods Microbiology Micrococcus Phenazines - metabolism Physiological aspects Polymerase Chain Reaction Retrospective Studies Sensitivity and Specificity Sepsis Staphylococcus Staphylococcus aureus Staphylococcus infections United States
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