Bone marrow aspiration concentrate and platelet rich plasma for osteochondral repair in a porcine osteochondral defect model

Bone marrow aspiration concentrate (BMAC) may possess a high potency for cartilage and osseous defect healing because it contains stem cells and multiple growth factors. Alternatively, platelet rich plasma (PRP), which contains a cocktail of multiple growth factors released from enriched activated t...

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Veröffentlicht in:	PloS one 2013-08, Vol.8 (8), p.e71602-e71602
Hauptverfasser:	Betsch, Marcel, Schneppendahl, Johannes, Thuns, Simon, Herten, Monika, Sager, Martin, Jungbluth, Pascal, Hakimi, Mohssen, Wild, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - metabolism Animals Anticoagulants Autografts Biocompatibility Biology Blood Blood levels Blood platelets Bone and Bones - cytology Bone and Bones - pathology Bone and Bones - physiology Bone marrow Bone Marrow - physiology Bone Marrow Cells - cytology Bone Marrow Cells - metabolism Bone morphogenetic protein 2 Bone morphogenetic protein 7 Bone Regeneration - physiology Cartilage Cell Differentiation Chondrocytes - cytology Chondrocytes - metabolism Chondrogenesis - physiology Collagen (type II) Collagen Type II - metabolism Defects Deformities Engineering Female Femur Growth factors Hand surgery Healing Hospitals Hostages Immunohistochemistry Knee Laboratory animals Medicine Mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Mesenchyme Models, Animal Osteoblasts - cytology Osteoblasts - metabolism Osteogenesis - physiology Plasma Platelet-derived growth factor Platelet-Rich Plasma - physiology Platelets Skin & tissue grafts Stem cell transplantation Stem cells Surgery Swine Thrombocytes Toluidine Toluidine blue Transforming growth factor-b1 Transplants & implants Vascular endothelial growth factor Wound Healing
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