XRCC3 Thr241Met polymorphism and clinical outcomes of NSCLC patients receiving platinum-based chemotherapy: a systematic review and meta-analysis

X-ray repair cross-complementing protein 3 (XRCC3) is an essential gene involved in the double-strand break repair pathway. Published evidence has shown controversial results about the relationship between XRCC3 Thr241Met polymorphism and clinical outcomes of non-small cell lung cancer (NSCLC) patie...

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Veröffentlicht in:	PloS one 2013-08, Vol.8 (8), p.e69553-e69553
Hauptverfasser:	Shen, Xiao-yong, Lu, Fan-zhen, Wu, Yun, Zhao, Li-ting, Lin, Zhi-feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biology Cancer Cancer patients Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Carriers Chemotherapy Clinical outcomes Deoxyribonucleic acid DNA DNA repair DNA-Binding Proteins - genetics Double-strand break repair Ethnicity Genes Genetic aspects Hospitals Humans Lung cancer Lung diseases Lung Neoplasms - drug therapy Lung Neoplasms - genetics Medical ethics Medical prognosis Medicine Meta-analysis Non-small cell lung cancer Non-small cell lung carcinoma Patient outcomes Patients Platinum Platinum - therapeutic use Polymorphism Polymorphism, Genetic - genetics Repair Studies Surgery Survival Systematic review Thoracic surgery Treatment Outcome
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