The new face of the old molecules: crustin Pm4 and transglutaminase type I serving as rnps down-regulate astakine-mediated hematopoiesis

Astakine is an important cytokine that is involved in crustacean hematopoiesis. Interestingly, the protein levels of astakine increased dramatically in plasma of LPS-injected shrimp while mRNA levels remained unchanged. Here, we investigated the involvement of astakine 3'-untranslated region (U...

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Veröffentlicht in:	PloS one 2013-08, Vol.8 (8), p.e72793-e72793
Hauptverfasser:	Chang, Yun-Tsan, Lin, Cheng-Yung, Tsai, Che-Yiang, Siva, Vinu S, Chu, Chia-Ying, Tsai, Huai-Jen, Song, Yen-Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions 3' Untranslated Regions - physiology Animals Antimicrobial Cationic Peptides - genetics Antimicrobial Cationic Peptides - metabolism Arthropod Proteins - genetics Arthropod Proteins - metabolism Cell culture Cellular biology Cloning Crustaceans Decapoda (Crustacea) - genetics Decapoda (Crustacea) - metabolism Down-Regulation - physiology Electrophoretic mobility Gene expression Granulocytes Hematopoiesis Hematopoiesis - physiology Hemocytes Hemocytes - cytology Hemocytes - metabolism Homeostasis Immunology Life sciences Lipopolysaccharides mRNA stability Penaeus monodon Post-transcription Proteins Regulatory sequences Reporter gene Ribonucleic acid Ribonucleoproteins - genetics Ribonucleoproteins - metabolism RNA RNA Stability - physiology RNA-binding protein Sf9 Cells Spodoptera Transglutaminases - genetics Transglutaminases - metabolism Trends Tumor necrosis factor-TNF Vascular Endothelial Growth Factor, Endocrine-Gland-Derived - biosynthesis Vascular Endothelial Growth Factor, Endocrine-Gland-Derived - genetics Zoology
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