Regulation of nucleotide excision repair by nuclear lamin b1

The nuclear lamins play important roles in the structural organization and function of the metazoan cell nucleus. Recent studies on B-type lamins identified a requirement for lamin B1 (LB1) in the regulation of cell proliferation in normal diploid cells. In order to further investigate the function...

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Veröffentlicht in:	PloS one 2013-07, Vol.8 (7), p.e69169-e69169
Hauptverfasser:	Butin-Israeli, Veronika, Adam, Stephen A, Goldman, Robert D
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Biocompatibility Biology Biomedical materials Cell cycle Cell Cycle - genetics Cell Cycle - radiation effects Cell Cycle Checkpoints - genetics Cell Cycle Checkpoints - radiation effects Cell growth Cell Line, Tumor Cell Proliferation Cellular Senescence - genetics Cellular Senescence - radiation effects Damage detection Deoxyribonucleic acid DNA DNA damage DNA Damage - genetics DNA Damage - radiation effects DNA Helicases - genetics DNA repair DNA Repair - genetics DNA Repair - physiology DNA Repair Enzymes - genetics DNA-Binding Proteins - genetics Enzyme-Linked Immunosorbent Assay Fibroblasts Fluorescent Antibody Technique Gene expression Humans Immunoblotting Immunoglobulins Irradiation Kinases Lamin Type B - genetics Lamin Type B - metabolism Lamins Molecular biology Mutation Nuclei Nuclei (cytology) Nucleotide excision repair Osteosarcoma Penicillin Poly-ADP-Ribose Binding Proteins Proliferating cell nuclear antigen Proliferating Cell Nuclear Antigen - genetics Proteins Radiation damage Repair RNA polymerase Rodents Senescence Signaling Stem cells Tumor cell lines Ultraviolet radiation Ultraviolet Rays
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