RecQL4 helicase amplification is involved in human breast tumorigenesis

Breast cancer occur both in hereditary and sporadic forms, and the later one comprises an overwhelming majority of breast cancer cases among women. Numerical and structural alterations involving chromosome 8, with loss of short arm (8p) and gain of long arm (8q), are frequently observed in breast ca...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-07, Vol.8 (7), p.e69600
Hauptverfasser:	Fang, Hongbo, Nie, Linghu, Chi, Zhenfen, Liu, Jing, Guo, Dan, Lu, Xuemei, Hei, Tom K, Balajee, Adayabalam S, Zhao, Yongliang
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Amplification Apoptosis Biology Bone cancer Breast cancer Breast Neoplasms - enzymology Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cancer Cancer research Cancer therapies Carcinogenesis - genetics Cell cycle Cell Line, Tumor Cell survival Cell Survival - genetics Chromosome 8 Chromosomes Deoxyribonucleic acid Development and progression DNA DNA helicase DNA repair Female Gene Amplification Gene expression Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Gene mutation Genes Genetic aspects Genetic Loci - genetics Genome, Human - genetics Genomics Humans In vivo methods and tests Inhibitor of Apoptosis Proteins - metabolism Laboratories Medical prognosis Medicine Metastasis mRNA Mutation Precision medicine Prostate RecQ Helicases - deficiency RecQ Helicases - genetics RNA RNA, Small Interfering - genetics Survival Survival factor Survivin Tissues Tumor cell lines Tumorigenesis Tumorigenicity Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!