Primary cilia are lost in preinvasive and invasive prostate cancer

Prostate cancer is the second most commonly diagnosed cancer in men worldwide. Little is known about the role of primary cilia in preinvasive and invasive prostate cancer. However, reduced cilia expression has been observed in human cancers including pancreatic cancer, renal cell carcinoma, breast c...

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Veröffentlicht in:	PloS one 2013-07, Vol.8 (7), p.e68521-e68521
Hauptverfasser:	Hassounah, Nadia B, Nagle, Ray, Saboda, Kathylynn, Roe, Denise J, Dalkin, Bruce L, McDermott, Kimberly M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged beta Catenin - metabolism Breast cancer Cancer Cell Movement Cell Nucleus - metabolism Cellular signal transduction Cholangiocarcinoma Cilia Cilia - metabolism Cilia - pathology Correlation Epithelial cells Fatty acids Humans Immunohistochemistry Invasiveness Keratin-5 - metabolism Kidney cancer Lesions Male Melanoma Microscopy, Confocal Middle Aged Neoplasm Grading Neoplasm Invasiveness Pancreatic cancer Pancreatic carcinoma Patients Prostate - metabolism Prostate - pathology Prostate - physiopathology Prostate cancer Prostatic intraepithelial neoplasia Prostatic Intraepithelial Neoplasia - metabolism Prostatic Intraepithelial Neoplasia - pathology Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Prostatic Neoplasms - physiopathology Proteins Renal cell carcinoma Signal transduction Signaling Tissues Wnt protein Wnt proteins Wnt Signaling Pathway β-Catenin
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